hemicentin-1 Inhibitors
Hemicentin-1 Inhibitors represent a fascinating class of chemical compounds that play a crucial role in modulating biological processes related to cellular adhesion and tissue development. Hemicentin-1, also known as HMCN1, is a large extracellular matrix protein found in various animal species, including humans. It is primarily associated with the formation and maintenance of structural integrity within tissues and organs. Inhibitors targeting hemicentin-1 have garnered considerable attention due to their impact on regulating cell adhesion and tissue remodeling processes.
Hemicentin-1 is characterized by its extensive repeat domains and interactions with other extracellular matrix proteins like fibulins and fibrillins. Inhibitors of hemicentin-1 function by disrupting these interactions, thereby influencing cell adhesion and migration. These compounds often possess specific binding motifs or regions that selectively interact with hemicentin-1, preventing it from performing its usual structural role. By inhibiting hemicentin-1, these compounds influence developmental processes, tissue repair mechanisms, and possibly play a role in disease states where aberrant tissue remodeling is a factor.
SEE ALSO...
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein can inhibit tyrosine kinases, which could alter cellular adhesion and signaling affecting hemicentin-1 functionality. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 is a PI3K inhibitor, which can modulate cell adhesion pathways by influencing AKT signaling, potentially affecting hemicentin-1. | ||||||
Wiskostatin | 253449-04-6 | sc-204399 sc-204399A sc-204399B sc-204399C | 1 mg 5 mg 25 mg 50 mg | $49.00 $124.00 $441.00 $828.00 | 4 | |
Wiskostatin inhibits N-WASP, thereby affecting actin polymerization, which is crucial for cell adhesion processes linked to hemicentin-1. | ||||||
CCG-1423 | 285986-88-1 | sc-205241 sc-205241A | 1 mg 5 mg | $30.00 $90.00 | 8 | |
CCG-1423 inhibits Rho signaling, impacting cytoskeletal organization and thus could affect hemicentin-1 mediated cell adhesion. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
Y-27632 is a ROCK inhibitor, reducing stress fiber formation and potentially impacting hemicentin-1's role in cell adhesion. | ||||||
PD173074 | 219580-11-7 | sc-202610 sc-202610A sc-202610B | 1 mg 5 mg 50 mg | $47.00 $143.00 $680.00 | 16 | |
PD173074 is an FGFR inhibitor that may affect extracellular matrix interactions and thereby influence hemicentin-1 functionality. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is a JNK inhibitor that can modulate cellular adhesion and survival pathways, potentially affecting hemicentin-1. | ||||||
ML-7 hydrochloride | 110448-33-4 | sc-200557 sc-200557A | 10 mg 50 mg | $91.00 $267.00 | 13 | |
ML7 inhibits myosin light chain kinase (MLCK) which is involved in cell contraction and adhesion, processes that hemicentin-1 may be part of. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
SB203580 is a p38 MAPK inhibitor, which can alter inflammation and cell adhesion, potentially influencing hemicentin-1 function. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin is a potent PI3K inhibitor which can affect various signaling pathways including those related to cell adhesion and hemicentin-1. | ||||||