HEATR7A Activators
The selected compounds, which can indirectly activate HEATR7A, serve as key players in diverse signaling pathways that likely intersect with the protein's expected cellular functions. Take insulin, for instance. By invigorating the PI3K/Akt pathway, insulin governs aspects of cellular growth and metabolism. Such governance sets the stage for influencing an array of cellular proteins, possibly encompassing HEATR7A, especially if its function lies in protein transport or folding. Furthermore, when molecules like EGCG and metformin stimulate the AMPK pathway, the aftermath encompasses a cascade of events that fine-tune cellular energy homeostasis, hinting at repercussions for proteins engaged in such intricate processes.
On another front, curcumin's ability to modulate the NF-kB pathway paints a picture of a cellular environment that is adaptive and fluid. This fluidity, affecting gene expression and protein function dynamics, can shape the operational landscape for proteins like HEATR7A. In a similar vein, retinoic acid's knack for regulating gene expression, alongside the epigenetic influence exerted by sodium butyrate and 5-Azacytidine, can redefine the expression levels and consequent roles of certain proteins, HEATR7A included. This redefinition means that under certain cellular conditions or states, HEATR7A's functionality might be more pronounced or modified. Finally, with the introduction of lithium and its influence on the Wnt/beta-catenin pathway, the impact is not just neuronal. Structural components of cells, integral to their foundation and integrity, can be reshaped, and proteins like HEATR7A, assuming they play a part in such structural dynamics, might experience altered states of activity or function.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $153.00 $1224.00 $12239.00 | 82 | |
Insulin activates the PI3K/Akt signaling pathway, which has broad implications on cellular metabolism and growth. Through Akt activation, it can influence the folding and transport machinery of the cell, which may include HEATR7A. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG modulates the AMPK pathway, which is known to regulate cellular energy homeostasis. Activation of AMPK can lead to downstream effects that might influence proteins like HEATR7A involved in cellular processes. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Through activation of SIRT1, resveratrol influences pathways involved in cell survival and stress responses. SIRT1 activation may impact the stability and function of proteins like HEATR7A. | ||||||
Metformin | 657-24-9 | sc-507370 | 10 mg | $77.00 | 2 | |
Metformin is an AMPK pathway activator. By enhancing AMPK signaling, it can modulate cellular energy balance, which could indirectly affect proteins like HEATR7A involved in energy-dependent cellular processes. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium acts on the Wnt/beta-catenin signaling pathway. While traditionally associated with neuronal processes, this pathway also influences cellular structure, which may impact proteins like HEATR7A. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin can modulate multiple signaling pathways, including the NF-kB pathway. By influencing this pathway, curcumin could indirectly affect protein functions like those associated with HEATR7A. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
A histone deacetylase inhibitor that can lead to changes in gene expression and potentially alter the cellular environment in a way that might affect HEATR7A's stability and function. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid modulates gene expression through the retinoic acid receptor. This can influence numerous cellular processes including those associated with HEATR7A. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A DNA methyltransferase inhibitor that causes DNA demethylation and can alter gene expression. Such epigenetic changes may affect the expression and function of proteins like HEATR7A. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Zinc is a cofactor for many proteins and is involved in numerous cellular functions, including those associated with protein folding and stability, potentially affecting HEATR7A. | ||||||