Date published: 2026-4-23

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HDGF Inhibitors

HDGF Inhibitors encompass a group of small molecules that are designed to selectively target the Hepatoma-Derived Growth Factor (HDGF) protein's activity. HDGF is a nuclear protein that plays critical roles in various cellular processes, including cell growth, proliferation, and DNA repair. The inhibitors within this chemical class are designed to interact with specific binding sites or functional regions of the HDGF protein, effectively obstructing its normal function within the cell. By doing so, these inhibitors aim to modulate cellular pathways and biological processes that involve HDGF, leading to implications in cellular homeostasis and physiological functions.

Researchers and drug developers are actively investigating the structure and properties of HDGF inhibitors to gain insights into their mode of action and their ability as valuable research tools to study HDGF-related cellular functions. As research progresses, a deeper understanding of the molecular interactions between HDGF and its inhibitors is being achieved, driving the advancement of this chemical class and its applications in various scientific investigations.

SEE ALSO...

Items 1 to 10 of 13 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Heparin

9005-49-6sc-507344
25 mg
$119.00
1
(0)

Heparin, a widely used anticoagulant drug, has been reported to inhibit the binding of HDGF to its receptor on the cell surface, thereby disrupting downstream signaling pathways.

Erlotinib Hydrochloride

183319-69-9sc-202154
sc-202154A
10 mg
25 mg
$75.00
$121.00
33
(1)

A tyrosine kinase inhibitor targeting EGFR. By inhibiting EGFR, it could reduce downstream signaling pathways that may involve HDGF, leading to decreased HDGF activity.

Suramin sodium

129-46-4sc-507209
sc-507209F
sc-507209A
sc-507209B
sc-507209C
sc-507209D
sc-507209E
50 mg
100 mg
250 mg
1 g
10 g
25 g
50 g
$152.00
$214.00
$728.00
$2601.00
$10965.00
$21838.00
$41096.00
5
(1)

Suramin is a polyanionic compound that has been shown to inhibit the growth factor-binding activity of HDGF, thereby reducing its effects on cellular functions.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$152.00
$479.00
$632.00
$1223.00
$2132.00
33
(3)

A histone deacetylase inhibitor, which can alter gene expression profiles, including those involving HDGF, thereby potentially reducing HDGF activity.

Sorafenib

284461-73-0sc-220125
sc-220125A
sc-220125B
5 mg
50 mg
500 mg
$57.00
$100.00
$250.00
129
(3)

A kinase inhibitor that targets multiple receptors including VEGFR and PDGFR. Its action could indirectly reduce HDGF activity by inhibiting pathways in which HDGF is involved.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

An mTOR inhibitor known to affect cell growth and proliferation, potentially influencing HDGF activity.

Bortezomib

179324-69-7sc-217785
sc-217785A
2.5 mg
25 mg
$135.00
$1085.00
115
(2)

A proteasome inhibitor that can affect various cellular processes, potentially leading to reduced HDGF activity.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

A natural compound known to affect multiple signaling pathways, potentially influencing HDGF activity.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

A PI3K inhibitor, potentially reducing HDGF activity by influencing the PI3K/Akt pathway.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

An inhibitor of JNK, which could indirectly influence HDGF activity by altering signaling pathways where HDGF is involved.