hCG_2015138 Inhibitors
The category of hCG_2015138 Inhibitors constitutes a specialized chemical class designed to selectively hinder the activity of the specific biomolecule identified as hCG_2015138. This chemical class represents a targeted approach within the fields of molecular biology and pharmacology, with the objective of unraveling the intricate roles played by hCG_2015138 in cellular pathways. The development of inhibitors for hCG_2015138 involves a meticulous analysis of the structural and functional characteristics of this biomolecule, enabling researchers to discern its molecular interactions and potential contributions to cellular processes.
Researchers engaged in the study of hCG_2015138 Inhibitors strive to design compounds that can effectively interfere with the activity or binding sites of hCG_2015138. The primary goal is to modulate the functions of this biomolecule, providing researchers with essential tools to investigate its specific roles and downstream effects within cellular systems. By disrupting the normal interactions of hCG_2015138, these inhibitors contribute to a deeper understanding of the underlying molecular mechanisms. The research surrounding hCG_2015138 Inhibitors not only unveils the functional aspects of the targeted biomolecule but also advances our broader comprehension of cellular processes, offering crucial insights into the complexities of molecular interactions and their implications in diverse biological contexts.
Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $88.00 $200.00 | 13 | |
Triptolide is a diterpene triepoxide that has been shown to inhibit the transcription of a wide range of genes. Its mechanism is believed to involve the inhibition of RNA polymerase II activity. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Actinomycin D binds to DNA and inhibits RNA polymerase, which is essential for the transcription of DNA into mRNA. By preventing mRNA synthesis, it broadly inhibits gene expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A is a histone deacetylase inhibitor that can cause hyperacetylation of histones, leading to changes in chromatin structure and affecting gene expression. | ||||||
Puromycin dihydrochloride | 58-58-2 | sc-108071 sc-108071B sc-108071C sc-108071A | 25 mg 250 mg 1 g 50 mg | $40.00 $210.00 $816.00 $65.00 | 394 | |
Puromycin is an aminonucleoside antibiotic from the aminoglycoside family that causes premature chain termination during translation. While not directly an inhibitor of gene expression, it can reduce protein levels by causing the release of incomplete polypeptide chains. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $260.00 $1029.00 | 26 | |
α-Amanitin is a toxin found in the Amanita phalloides mushroom, which specifically inhibits RNA polymerase II, thereby blocking mRNA synthesis and gene expression. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $57.00 $182.00 $92.00 | 21 | |
Camptothecin is a topoisomerase I inhibitor, leading to DNA damage and potential inhibition of transcription and replication processes. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $68.00 | 2 | |
Chloroquine can intercalate into DNA, which may inhibit DNA replication and RNA transcription. Although known as an antimalarial, its intercalating activity suggests it can also broadly affect gene expression. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $54.00 | 6 | |
Mithramycin A binds to GC-rich sequences in DNA, interfering with transcription factor binding and RNA polymerase progression, thereby inhibiting gene transcription. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $42.00 $185.00 $310.00 $650.00 | 6 | |
DRB is an adenosine analog that inhibits RNA synthesis by targeting RNA polymerase II. This inhibition can affect the expression of most genes transcribed by this enzyme. | ||||||
Flavopiridol | 146426-40-6 | sc-202157 sc-202157A | 5 mg 25 mg | $78.00 $254.00 | 41 | |
Flavopiridol inhibits CDKs (cyclin-dependent kinases), which are necessary for cell cycle progression and regulation of transcription. By inhibiting CDK9, it can reduce the phosphorylation of RNA polymerase II, thus hindering the elongation phase of transcription. | ||||||