Date published: 2026-4-1

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H2-T24 Inhibitors

H2-T24 inhibitors constitute a specific class of chemical compounds designed to modulate the activity of the H2-T24 protein. H2-T24, also known as histocompatibility 2, T region locus 24, is a protein found within the major histocompatibility complex (MHC) system, particularly in mice. The MHC system plays a central role in the immune response by presenting antigenic peptides to T cells, allowing the immune system to recognize and respond to foreign pathogens effectively. H2-T24, similar to other MHC molecules, is intricately involved in the process of antigen presentation, which is a fundamental mechanism that enables the body to initiate immune responses against infections. The development of H2-T24 inhibitors is primarily driven by the goal of selectively interacting with the H2-T24 protein, potentially influencing its antigen-presenting activity and impacting immune recognition processes.

Typically, H2-T24 inhibitors consist of small molecules or chemical compounds that are specifically engineered to bind to H2-T24, targeting either its active site or allosteric sites. This interaction can lead to the modulation of H2-T24's behavior, potentially affecting its ability to present antigenic peptides to T cells and, consequently, influencing the immune response against foreign antigens. Researchers are dedicated to unraveling the molecular mechanisms and functions of H2-T24 within the MHC system, aiming to gain insights into the complex immune recognition processes. The development of H2-T24 inhibitors represents an ongoing and dynamic area of research within the fields of immunology and molecular pharmacology, contributing to a deeper understanding of the immune system's functioning and its role in detecting and responding to foreign antigens.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Rifampicin

13292-46-1sc-200910
sc-200910A
sc-200910B
sc-200910C
1 g
5 g
100 g
250 g
$97.00
$328.00
$676.00
$1467.00
6
(1)

Binds to RNA polymerase and inhibits RNA synthesis, potentially reducing H2-T24 mRNA levels.

α-Amanitin

23109-05-9sc-202440
sc-202440A
1 mg
5 mg
$269.00
$1050.00
26
(2)

Inhibits RNA polymerase II and III, which could lead to a decrease in transcription of H2-T24.

Mitomycin C

50-07-7sc-3514A
sc-3514
sc-3514B
2 mg
5 mg
10 mg
$66.00
$101.00
$143.00
85
(5)

Forms cross-links within DNA, inhibiting DNA replication and transcription, which might reduce H2-T24 expression.

Triptolide

38748-32-2sc-200122
sc-200122A
1 mg
5 mg
$90.00
$204.00
13
(1)

Has been shown to inhibit the transcription of various genes, which could include H2-T24.

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$74.00
$243.00
$731.00
$2572.00
$21848.00
53
(3)

Intercalates into DNA and prevents the transcription elongation process, potentially reducing mRNA levels of H2-T24.

DRB

53-85-0sc-200581
sc-200581A
sc-200581B
sc-200581C
10 mg
50 mg
100 mg
250 mg
$43.00
$189.00
$316.00
$663.00
6
(1)

Inhibits RNA polymerase II phosphorylation, thereby affecting mRNA production, possibly including H2-T24.

Flavopiridol

146426-40-6sc-202157
sc-202157A
5 mg
25 mg
$78.00
$259.00
41
(3)

Inhibits cyclin-dependent kinases, affecting transcription and potentially reducing H2-T24 mRNA synthesis.

Oxamflatin

151720-43-3sc-205960
sc-205960A
1 mg
5 mg
$151.00
$470.00
4
(1)

A histone deacetylase inhibitor that can alter chromatin structure and downregulate gene expression.

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

A DNA methyltransferase inhibitor that can cause DNA demethylation and affect gene expression.

Camptothecin

7689-03-4sc-200871
sc-200871A
sc-200871B
50 mg
250 mg
100 mg
$58.00
$186.00
$94.00
21
(2)

Inhibits topoisomerase I, leading to DNA damage and potentially affecting transcription and replication processes.