Date published: 2026-4-1

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H2-M5 Inhibitors

H2-M5 inhibitors form a specific class of chemical compounds designed to modulate the activity of the H2-M5 protein. H2-M5, also known as histocompatibility 2, M region locus 5, is a protein found within the major histocompatibility complex (MHC) system in mice. The MHC system is crucial for the immune response, as it plays a central role in presenting antigenic peptides to T cells, enabling the immune system to recognize and respond to foreign pathogens effectively. H2-M5, much like other MHC molecules, is intricately involved in the process of antigen presentation, a fundamental mechanism that allows the body to initiate immune responses against infections. The development of H2-M5 inhibitors is rooted in the primary objective of selectively interacting with the H2-M5 protein, potentially influencing its antigen-presenting activity and impacting immune recognition processes.

Typically, H2-M5 inhibitors are composed of small molecules or chemical compounds specifically engineered to bind to H2-M5, targeting either its active site or allosteric sites. This interaction can lead to the modulation of H2-M5's behavior, potentially affecting its ability to present antigenic peptides to T cells and, consequently, influencing the immune response against foreign antigens. Researchers are primarily dedicated to unraveling the molecular mechanisms and functions of H2-M5 within the MHC system, aiming to gain insights into the complex immune recognition processes. The development of H2-M5 inhibitors represents an active and evolving area of research within the fields of immunology and molecular pharmacology, contributing to a deeper understanding of the immune system's functioning and its role in detecting and responding to foreign antigens.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

Inhibits mTOR, which is important for protein synthesis and cell growth, potentially reducing overall protein expression levels.

Geldanamycin

30562-34-6sc-200617B
sc-200617C
sc-200617
sc-200617A
100 µg
500 µg
1 mg
5 mg
$39.00
$59.00
$104.00
$206.00
8
(1)

Binds to heat shock protein 90 (Hsp90) and disrupts its function, affecting the stability and function of numerous client proteins.

Cycloheximide

66-81-9sc-3508B
sc-3508
sc-3508A
100 mg
1 g
5 g
$41.00
$84.00
$275.00
127
(6)

Inhibits eukaryotic protein synthesis by interfering with the translocation step on ribosomes.

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$74.00
$243.00
$731.00
$2572.00
$21848.00
53
(3)

Interferes with DNA-dependent RNA synthesis by inhibiting RNA polymerase after forming a complex with DNA.

Chloroquine

54-05-7sc-507304
250 mg
$69.00
2
(0)

Inhibits DNA and RNA polymerase enzymes and is known to intercalate into DNA, affecting gene expression.

Mithramycin A

18378-89-7sc-200909
1 mg
$55.00
6
(1)

Binds to DNA and inhibits RNA synthesis, thus affecting gene transcription.

Aphidicolin

38966-21-1sc-201535
sc-201535A
sc-201535B
1 mg
5 mg
25 mg
$84.00
$306.00
$1104.00
30
(3)

Inhibits DNA polymerase, particularly in eukaryotes, and thus can suppress DNA replication and gene expression.

Etoposide (VP-16)

33419-42-0sc-3512B
sc-3512
sc-3512A
10 mg
100 mg
500 mg
$51.00
$231.00
$523.00
63
(1)

Stabilizes the DNA-topoisomerase II complex, which can cause DNA breaks and interfere with transcription.

1-β-D-Arabinofuranosylcytosine

147-94-4sc-201628
sc-201628A
sc-201628B
sc-201628C
sc-201628D
1 g
5 g
25 g
100 g
250 g
$150.00
$263.00
$518.00
$731.00
$1461.00
1
(1)

A nucleoside analog that gets incorporated into DNA, inhibiting DNA polymerase and thus gene expression.

Puromycin

53-79-2sc-205821
sc-205821A
10 mg
25 mg
$166.00
$322.00
436
(1)

Mimics the aminoacyl end of tRNA and interferes with translation termination and ribosome release.