H2-M11 inhibitors belong to a specific category of chemical compounds designed to modulate the activity of the H2-M11 protein. H2-M11, also referred to as histocompatibility 2, M region locus 11, is a protein that plays an integral role within the major histocompatibility complex (MHC) system in mice. The MHC system serves as a cornerstone of the immune response by presenting antigenic peptides to T cells, thus allowing the immune system to recognize and respond to foreign pathogens effectively. H2-M11, much like other MHC molecules, participates in the intricate process of antigen presentation, which is fundamental for initiating immune responses against infections. The development of H2-M11 inhibitors is rooted in the primary goal of selectively interacting with the H2-M11 protein, potentially influencing its antigen-presenting activity and impacting immune recognition processes.
Typically, H2-M11 inhibitors consist of small molecules or chemical compounds that are engineered to bind specifically to H2-M11, targeting either its active site or allosteric sites. This interaction has the potential to modify H2-M11's behavior, potentially affecting its ability to present antigenic peptides to T cells and, consequently, influencing the immune response against foreign antigens. Researchers are dedicated to elucidating the molecular mechanisms and functions of H2-M11 within the MHC system, aiming to gain insights into the complex immune recognition processes. The development of H2-M11 inhibitors represents an ongoing area of research within the fields of immunology and molecular pharmacology, contributing to a deeper understanding of the immune system's functioning and its role in detecting and responding to foreign antigens.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A cytidine analog that incorporates into DNA and RNA and inhibits DNA methyltransferase, potentially affecting gene expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
A histone deacetylase inhibitor which can change chromatin structure and activate transcription of some genes. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
An mTOR inhibitor which can affect cellular growth pathways and downstream gene expression. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $82.00 $216.00 $416.00 | 48 | |
An inhibitor of the TGF-beta receptor which can alter transcriptional responses and gene expression. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
A MAP kinase inhibitor which interferes with the MAPK/ERK pathway and can modify gene expression. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
A PI3K inhibitor that may modify AKT signaling and affect various cellular processes including transcription. | ||||||
Cyclopamine | 4449-51-8 | sc-200929 sc-200929A | 1 mg 5 mg | $94.00 $208.00 | 19 | |
Inhibits the Hedgehog signaling pathway which may influence gene expression patterns in development. | ||||||
Histone Lysine Methyltransferase Inhibitor Inhibitor | 935693-62-2 (free base) | sc-202651 | 5 mg | $151.00 | 4 | |
A G9a histone methyltransferase inhibitor that may alter histone methylation and gene expression. | ||||||
RG 108 | 48208-26-0 | sc-204235 sc-204235A | 10 mg 50 mg | $131.00 $515.00 | 2 | |
A DNA methyltransferase inhibitor that does not incorporate into DNA but blocks the active site. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
An HDAC inhibitor that can cause cell cycle arrest and modify gene expression. | ||||||