Date published: 2026-2-14

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H2-M11 Inhibitors

H2-M11 inhibitors belong to a specific category of chemical compounds designed to modulate the activity of the H2-M11 protein. H2-M11, also referred to as histocompatibility 2, M region locus 11, is a protein that plays an integral role within the major histocompatibility complex (MHC) system in mice. The MHC system serves as a cornerstone of the immune response by presenting antigenic peptides to T cells, thus allowing the immune system to recognize and respond to foreign pathogens effectively. H2-M11, much like other MHC molecules, participates in the intricate process of antigen presentation, which is fundamental for initiating immune responses against infections. The development of H2-M11 inhibitors is rooted in the primary goal of selectively interacting with the H2-M11 protein, potentially influencing its antigen-presenting activity and impacting immune recognition processes.

Typically, H2-M11 inhibitors consist of small molecules or chemical compounds that are engineered to bind specifically to H2-M11, targeting either its active site or allosteric sites. This interaction has the potential to modify H2-M11's behavior, potentially affecting its ability to present antigenic peptides to T cells and, consequently, influencing the immune response against foreign antigens. Researchers are dedicated to elucidating the molecular mechanisms and functions of H2-M11 within the MHC system, aiming to gain insights into the complex immune recognition processes. The development of H2-M11 inhibitors represents an ongoing area of research within the fields of immunology and molecular pharmacology, contributing to a deeper understanding of the immune system's functioning and its role in detecting and responding to foreign antigens.

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

A cytidine analog that incorporates into DNA and RNA and inhibits DNA methyltransferase, potentially affecting gene expression.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$152.00
$479.00
$632.00
$1223.00
$2132.00
33
(3)

A histone deacetylase inhibitor which can change chromatin structure and activate transcription of some genes.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

An mTOR inhibitor which can affect cellular growth pathways and downstream gene expression.

SB 431542

301836-41-9sc-204265
sc-204265A
sc-204265B
1 mg
10 mg
25 mg
$82.00
$216.00
$416.00
48
(1)

An inhibitor of the TGF-beta receptor which can alter transcriptional responses and gene expression.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$40.00
$92.00
212
(2)

A MAP kinase inhibitor which interferes with the MAPK/ERK pathway and can modify gene expression.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

A PI3K inhibitor that may modify AKT signaling and affect various cellular processes including transcription.

Cyclopamine

4449-51-8sc-200929
sc-200929A
1 mg
5 mg
$94.00
$208.00
19
(1)

Inhibits the Hedgehog signaling pathway which may influence gene expression patterns in development.

Histone Lysine Methyltransferase Inhibitor Inhibitor

935693-62-2 (free base)sc-202651
5 mg
$151.00
4
(1)

A G9a histone methyltransferase inhibitor that may alter histone methylation and gene expression.

RG 108

48208-26-0sc-204235
sc-204235A
10 mg
50 mg
$131.00
$515.00
2
(1)

A DNA methyltransferase inhibitor that does not incorporate into DNA but blocks the active site.

Suberoylanilide Hydroxamic Acid

149647-78-9sc-220139
sc-220139A
100 mg
500 mg
$133.00
$275.00
37
(2)

An HDAC inhibitor that can cause cell cycle arrest and modify gene expression.