Date published: 2026-4-1

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H2-M10.5 Inhibitors

H2-M10.5 inhibitors constitute a specific class of chemical compounds designed to modulate the activity of the H2-M10.5 protein. H2-M10.5, also known as histocompatibility 2, M region locus 10.5, is a protein that is part of the major histocompatibility complex (MHC) in mice. The MHC plays a crucial role in the immune response by presenting antigenic peptides to T cells, enabling the immune system to recognize and respond to foreign pathogens effectively. H2-M10.5, like other MHC molecules, participates in the complex process of antigen presentation, a fundamental mechanism that allows the body to initiate immune responses against infections. The development of H2-M10.5 inhibitors is primarily aimed at selectively interacting with the H2-M10.5 protein, potentially influencing its antigen-presenting activity and affecting immune recognition processes.

Typically, H2-M10.5 inhibitors are composed of small molecules or chemical compounds specifically designed to bind to H2-M10.5, targeting either its active site or allosteric sites. This interaction can lead to the modulation of H2-M10.5's behavior, potentially affecting its ability to present antigenic peptides to T cells and, consequently, influencing the immune response against foreign antigens. Researchers are primarily dedicated to unraveling the molecular mechanisms and functions of H2-M10.5 within the MHC system and how inhibiting its activity with these compounds may provide insights into the complex immune recognition processes. The development of H2-M10.5 inhibitors represents an active and evolving area of research within the fields of immunology and molecular pharmacology, contributing to a deeper understanding of the immune system's functioning and its role in detecting and responding to foreign antigens.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$74.00
$243.00
$731.00
$2572.00
$21848.00
53
(3)

Binds to DNA and inhibits RNA polymerase, thereby preventing RNA synthesis and gene expression.

Mitomycin C

50-07-7sc-3514A
sc-3514
sc-3514B
2 mg
5 mg
10 mg
$66.00
$101.00
$143.00
85
(5)

Forms crosslinkages within DNA, which can interfere with DNA replication and RNA transcription, leading to reduced gene expression.

Puromycin

53-79-2sc-205821
sc-205821A
10 mg
25 mg
$166.00
$322.00
436
(1)

Causes premature chain termination during protein synthesis, affecting overall gene expression.

Anisomycin

22862-76-6sc-3524
sc-3524A
5 mg
50 mg
$99.00
$259.00
36
(2)

Inhibits peptide bond formation by binding to the 60S ribosomal subunit, reducing protein synthesis and indirectly affecting gene expression.

α-Sarcin

86243-64-3sc-204427
1 mg
$462.00
6
(0)

A ribosome-inactivating protein that cleaves a specific adenine from rRNA, inhibiting protein synthesis and thus gene expression.

Fusidic acid

6990-06-3sc-215065
1 g
$292.00
(0)

Binds to elongation factor G on the ribosome, inhibiting protein synthesis and indirectly gene expression.

Homoharringtonine

26833-87-4sc-202652
sc-202652A
sc-202652B
1 mg
5 mg
10 mg
$52.00
$125.00
$182.00
11
(1)

Inhibits protein synthesis by blocking the peptidyl transferase reaction, leading to decreased gene expression.

Neomycin sulfate

1405-10-3sc-3573
sc-3573A
1 g
5 g
$27.00
$35.00
20
(5)

Binds to ribosomal RNA and inhibits protein synthesis, indirectly affecting gene expression.

Mycophenolic acid

24280-93-1sc-200110
sc-200110A
100 mg
500 mg
$69.00
$266.00
8
(1)

Inhibits inosine monophosphate dehydrogenase, leading to depletion of guanosine nucleotides and potentially reducing gene expression.

Brefeldin A

20350-15-6sc-200861C
sc-200861
sc-200861A
sc-200861B
1 mg
5 mg
25 mg
100 mg
$31.00
$53.00
$124.00
$374.00
25
(3)

Disrupts transport within the Golgi apparatus, which can indirectly affect cellular processes including gene expression.