Date published: 2025-12-18

1-800-457-3801

SCBT Portrait Logo
Seach Input

H2-M10.4 Inhibitors

H2-M10.4 inhibitors belong to a specific category of chemical compounds designed to modulate the activity of the H2-M10.4 protein. H2-M10.4, also known as histocompatibility 2, M region locus 10.4, is a protein that is part of the major histocompatibility complex (MHC) system in mice. The MHC plays a critical role in the immune response by presenting antigenic peptides to T cells, allowing the immune system to recognize and respond to foreign pathogens. H2-M10.4, similar to other MHC molecules, is involved in the intricate process of antigen presentation, a fundamental mechanism that enables the body to initiate immune responses against infections. The development of H2-M10.4 inhibitors is motivated by the primary goal of selectively interacting with the H2-M10.4 protein, potentially influencing its antigen-presenting activity and impacting immune recognition processes.

Typically, H2-M10.4 inhibitors consist of small molecules or chemical compounds specifically designed to bind to H2-M10.4, targeting either its active site or allosteric sites. This interaction can lead to the modulation of H2-M10.4's behavior, potentially affecting its ability to present antigenic peptides to T cells and, consequently, influencing the immune response against foreign antigens. Researchers are primarily dedicated to unraveling the molecular mechanisms and functions of H2-M10.4 within the MHC system and how inhibiting its activity with these compounds may provide insights into the intricate immune recognition processes. The development of H2-M10.4 inhibitors represents an active area of research within the fields of immunology and molecular pharmacology, contributing to a deeper understanding of the immune system's functioning and its role in detecting and responding to foreign antigens.

SEE ALSO...

Items 1 to 10 of 12 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

A nucleoside analog of cytidine that can be incorporated into DNA and RNA, potentially disrupting DNA methylation and thus gene expression patterns.

Chloroquine

54-05-7sc-507304
250 mg
$68.00
2
(0)

Known to intercalate into DNA, which may disrupt DNA replication and RNA synthesis, possibly leading to reduced gene expression.

Camptothecin

7689-03-4sc-200871
sc-200871A
sc-200871B
50 mg
250 mg
100 mg
$57.00
$182.00
$92.00
21
(2)

A topoisomerase I inhibitor that prevents DNA relaxation, which is necessary for transcription, potentially reducing gene expression.

Fluorouracil

51-21-8sc-29060
sc-29060A
1 g
5 g
$36.00
$149.00
11
(1)

A uracil analog that interferes with nucleotide synthesis and can be incorporated into RNA, potentially disrupting gene expression.

Etoposide (VP-16)

33419-42-0sc-3512B
sc-3512
sc-3512A
10 mg
100 mg
500 mg
$32.00
$170.00
$385.00
63
(1)

Inhibits topoisomerase II, leading to DNA strand breaks and potentially affecting transcription processes, reducing gene expression.

DRB

53-85-0sc-200581
sc-200581A
sc-200581B
sc-200581C
10 mg
50 mg
100 mg
250 mg
$42.00
$185.00
$310.00
$650.00
6
(1)

Inhibits RNA polymerase II, potentially leading to a decrease in mRNA synthesis and gene expression.

α-Amanitin

23109-05-9sc-202440
sc-202440A
1 mg
5 mg
$260.00
$1029.00
26
(2)

A potent inhibitor of RNA polymerase II, leading to a direct decrease in mRNA synthesis and gene expression.

Triptolide

38748-32-2sc-200122
sc-200122A
1 mg
5 mg
$88.00
$200.00
13
(1)

Known to inhibit the transcription of various genes, potentially affecting gene expression through multiple pathways.

Homoharringtonine

26833-87-4sc-202652
sc-202652A
sc-202652B
1 mg
5 mg
10 mg
$51.00
$123.00
$178.00
11
(1)

Can inhibit protein synthesis by preventing the initial elongation step of translation, indirectly affecting gene expression.

Geldanamycin

30562-34-6sc-200617B
sc-200617C
sc-200617
sc-200617A
100 µg
500 µg
1 mg
5 mg
$38.00
$58.00
$102.00
$202.00
8
(1)

Binds to Hsp90 and inhibits its function, which might indirectly reduce the stability and function of several client proteins that regulate gene expression.