H2-M10.1 inhibitors belong to a specific class of chemical compounds designed to modulate the activity of the H2-M10.1 protein. H2-M10.1, also known as histocompatibility 2, M region locus 10.1, is a protein that plays a significant role in the major histocompatibility complex (MHC) system, particularly in mice. The MHC is a crucial component of the immune system responsible for presenting antigenic peptides to T cells, thereby facilitating the recognition and immune response against foreign pathogens. H2-M10.1, like other MHC molecules, is involved in the intricate process of antigen presentation, which is pivotal for the body's ability to mount immune responses against infections. H2-M10.1 inhibitors are specifically developed to interact with the H2-M10.1 protein, with the aim of potentially influencing its antigen-presenting activity and impacting the immune response in the context of MHC-associated processes.
H2-M10.1 inhibitors typically consist of small molecules or chemical compounds engineered to bind selectively to H2-M10.1, targeting either its active site or allosteric sites. This interaction can lead to the modulation of H2-M10.1's behavior, potentially affecting its ability to present antigenic peptides to T cells and influence immune recognition processes. Researchers are primarily dedicated to understanding the molecular mechanisms and functions of H2-M10.1 within the MHC system and how inhibiting its activity with these compounds may provide insights into the complex immune response mechanisms. The development of H2-M10.1 inhibitors represents an active area of research within the field of immunology and molecular pharmacology, contributing to our broader comprehension of the immune system and its role in recognizing and defending against foreign antigens.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A inhibits histone deacetylases, potentially leading to hyperacetylation of histones and altered expression of certain genes. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $85.00 | 9 | |
Valproic Acid is a known inhibitor of histone deacetylase, which can change chromatin structure and gene expression. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
Sodium Butyrate acts as a histone deacetylase inhibitor, affecting chromatin remodeling and gene transcription. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
Vorinostat, another histone deacetylase inhibitor, can influence gene expression by altering chromatin accessibility. | ||||||
MS-275 | 209783-80-2 | sc-279455 sc-279455A sc-279455B | 1 mg 5 mg 25 mg | $24.00 $88.00 $208.00 | 24 | |
Entinostat is a histone deacetylase inhibitor, which may result in changes to chromatin structure and gene expression. | ||||||
Panobinostat | 404950-80-7 | sc-208148 | 10 mg | $196.00 | 9 | |
Panobinostat is a potent histone deacetylase inhibitor, modifying the chromatin structure and potentially affecting transcription. | ||||||
Romidepsin | 128517-07-7 | sc-364603 sc-364603A | 1 mg 5 mg | $214.00 $622.00 | 1 | |
Romidepsin is a histone deacetylase inhibitor, which can lead to changes in gene expression profiles. | ||||||
Mocetinostat | 726169-73-9 | sc-364539 sc-364539B sc-364539A | 5 mg 10 mg 50 mg | $210.00 $242.00 $1434.00 | 2 | |
Mocetinostat inhibits histone deacetylases, potentially altering gene expression through chromatin remodeling. | ||||||
Belinostat | 414864-00-9 | sc-269851 sc-269851A | 10 mg 100 mg | $153.00 $561.00 | ||
Belinostat is a histone deacetylase inhibitor that can change the expression levels of various genes. | ||||||
Chidamide | 743420-02-2 | sc-364462 sc-364462A sc-364462B | 1 mg 5 mg 25 mg | $61.00 $245.00 $1173.00 | ||
Chidamide selectively inhibits histone deacetylase, which can affect chromatin organization and gene transcription. |