GST Inhibitors
SEE ALSO...
Items 11 to 18 of 18 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin, a natural compound found in turmeric, has been reported to inhibit GSTs indirectly by interfering with their gene expression and activity. | ||||||
Butein | 487-52-5 | sc-202510 sc-202510A | 5 mg 50 mg | $175.00 $312.00 | 8 | |
Butein, a flavonoid compound, exhibits unique interactions with glutathione S-transferases (GSTs) through its electrophilic sites, facilitating conjugation reactions. Its distinct molecular structure allows for selective binding to various GST isoforms, enhancing its reactivity. The compound's ability to form stable conjugates with glutathione underscores its role in cellular detoxification pathways. Furthermore, its hydrophilic and lipophilic balance influences its bioavailability and interaction with cellular membranes. | ||||||
Caffeic Acid | 331-39-5 | sc-200499 sc-200499A | 1 g 5 g | $32.00 $62.00 | 1 | |
Caffeic acid, a phenolic compound found in coffee and other foods, has been studied for its inhibitory effects on GSTs, which might contribute to its potential health benefits. | ||||||
ETI | 13488-22-7 | sc-200762 sc-200762A | 1 mg 10 mg | $85.00 $611.00 | ||
ETI, an acid halide, demonstrates remarkable reactivity through its electrophilic carbonyl group, which readily engages in nucleophilic attack by thiols and amines. This property enables it to participate in acylation reactions, forming stable amides and esters. The compound's unique steric configuration influences its reaction kinetics, allowing for selective interactions with various nucleophiles. Additionally, its polar nature enhances solubility in organic solvents, facilitating diverse synthetic applications. | ||||||
β-Estradiol 3,17-disulfate dipotassium salt | 17046-60-5 | sc-227988 | 25 mg | $105.00 | ||
β-Estradiol 3,17-disulfate dipotassium salt exhibits intriguing properties as a GST, characterized by its ability to undergo conjugation reactions with glutathione. This interaction is facilitated by its sulfate groups, which enhance electrophilicity, promoting rapid detoxification processes. The compound's unique structural features allow for specific binding interactions, influencing enzyme activity and substrate specificity. Its solubility in aqueous environments further supports its role in biochemical pathways, enhancing its reactivity in cellular systems. | ||||||
Cibacron Blue | 84166-13-2 | sc-507477 | 10 mg | $77.00 | ||
This compound competitively inhibits GST activity by binding to the substrate-binding site of the enzyme. | ||||||
α-Lipoic Acid | 1077-28-7 | sc-202032 sc-202032A sc-202032B sc-202032C sc-202032D | 5 g 10 g 250 g 500 g 1 kg | $69.00 $122.00 $212.00 $380.00 $716.00 | 3 | |
Alpha lipoic acid is an antioxidant that has been investigated for its ability to modulate GST activity and protect against oxidative stress. | ||||||
L-Buthionine sulfoximine | 83730-53-4 | sc-200824 sc-200824A sc-200824B sc-200824C | 500 mg 1 g 5 g 10 g | $286.00 $442.00 $1532.00 $2975.00 | 26 | |
BSO is a compound that indirectly targets GSTs by inhibiting the synthesis of glutathione, the cofactor required for GST activity. | ||||||