granzyme G Inhibitors
Granzyme G inhibitors belong to a class of chemical compounds designed to modulate the activity of the enzyme granzyme G. Granzyme G is a member of the granzyme family of serine proteases, which play a crucial role in the immune system, particularly within cytotoxic lymphocytes like natural killer (NK) cells and cytotoxic T lymphocytes (CTLs). These enzymes are key effectors of the immune response against infected or abnormal cells, as they are involved in inducing apoptosis, a controlled form of cell death, in target cells. Granzyme G, in particular, is known for its ability to cleave and activate pro-caspase-3, an important mediator of apoptosis. By inhibiting granzyme G, researchers can gain insights into the regulation of immune responses and the mechanisms underlying cytotoxicity.
Understanding the role of granzyme G in the immune system is essential for comprehending the intricacies of cell-mediated immunity. Granzyme G inhibitors are valuable tools for researchers studying immune responses, as they allow for the manipulation of specific components within the cytotoxic pathway. By dissecting the function of granzyme G and its regulation, scientists aim to broaden their knowledge of immunology and develop strategies to modulate immune responses for various medical purposes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Aprotinin | 9087-70-1 | sc-3595 sc-3595A sc-3595B | 10 mg 100 mg 1 g | $112.00 $408.00 $3000.00 | 51 | |
A broad-spectrum serine protease inhibitor which might inhibit the enzymatic activity of granzyme G. | ||||||
Leupeptin hemisulfate | 103476-89-7 | sc-295358 sc-295358A sc-295358D sc-295358E sc-295358B sc-295358C | 5 mg 25 mg 50 mg 100 mg 500 mg 10 mg | $73.00 $148.00 $316.00 $499.00 $1427.00 $101.00 | 19 | |
Inhibits serine and cysteine proteases, potentially affecting granzyme G's proteolytic activity. | ||||||
AEBSF hydrochloride | 30827-99-7 | sc-202041 sc-202041A sc-202041B sc-202041C sc-202041D sc-202041E | 50 mg 100 mg 5 g 10 g 25 g 100 g | $65.00 $122.00 $428.00 $851.00 $1873.00 $4994.00 | 33 | |
A serine protease inhibitor which may inhibit the enzymatic activity of granzyme G. | ||||||
E-64 | 66701-25-5 | sc-201276 sc-201276A sc-201276B | 5 mg 25 mg 250 mg | $281.00 $947.00 $1574.00 | 14 | |
Cysteine protease inhibitor which might affect related granzymes or serine proteases indirectly. | ||||||
Phenylmethylsulfonyl Fluoride | 329-98-6 | sc-3597 sc-3597A | 1 g 100 g | $50.00 $697.00 | 92 | |
A serine protease inhibitor that could potentially inhibit granzyme G activity. | ||||||
Chymostatin | 9076-44-2 | sc-202541 sc-202541A sc-202541B sc-202541C sc-202541D | 5 mg 10 mg 25 mg 50 mg 100 mg | $156.00 $260.00 $640.00 $1186.00 $2270.00 | 3 | |
Broad-spectrum protease inhibitor that might inhibit granzyme G. | ||||||
Elastatinal | 51798-45-9 | sc-201272 sc-201272A | 5 mg 25 mg | $87.00 $346.00 | 4 | |
An inhibitor of elastase-like serine proteases, it might influence granzyme G's activity. | ||||||
Gabexate mesylate | 56974-61-9 | sc-215066 | 5 mg | $100.00 | ||
Serine protease inhibitor with potential to inhibit granzyme G. | ||||||
Benzamidine | 618-39-3 | sc-233933 | 10 g | $292.00 | 1 | |
A reversible inhibitor of trypsin-like serine proteases, it might affect granzyme G. | ||||||