GPR55 Activators
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Palmitoylethanolamide | 544-31-0 | sc-202754 sc-202754A sc-202754B sc-202754C sc-202754D | 10 mg 50 mg 500 mg 1 g 10 g | $78.00 $238.00 $2050.00 $3274.00 $16330.00 | ||
Palmitoylethanolamide acts as a modulator of GPR55, engaging in specific molecular interactions that influence receptor signaling pathways. Its unique fatty acid amide structure facilitates selective binding, promoting receptor desensitization and altering intracellular calcium levels. The compound's lipid-like properties enhance membrane permeability, allowing for rapid cellular uptake. Additionally, its role in modulating inflammatory responses highlights its potential to influence various signaling cascades within the cell. | ||||||
AM-251 | 183232-66-8 | sc-200366A sc-200366 sc-200366B sc-200366C | 5 mg 10 mg 50 mg 100 mg | $71.00 $143.00 $612.00 $847.00 | 4 | |
Primarily a CB1 antagonist, AM-251 also acts as an inverse agonist at GPR55, leading to the inhibition of GPR55's constitutive activity and indirectly enhancing specific signaling pathways. | ||||||
Oleylethanolamide | 111-58-0 | sc-201400 sc-201400A | 10 mg 50 mg | $88.00 $190.00 | 1 | |
Oleylethanolamide serves as a selective modulator of GPR55, exhibiting unique interactions that fine-tune receptor activity. Its elongated fatty acid chain enhances hydrophobic interactions, promoting effective receptor engagement and subsequent downstream signaling. This compound influences lipid metabolism and energy homeostasis by modulating intracellular pathways, while its amphiphilic nature aids in membrane integration, facilitating swift cellular responses and dynamic signaling alterations. | ||||||
ABN-CBD | 22972-55-0 | sc-203488A sc-203488B sc-203488 sc-203488C | 1 mg 5 mg 10 mg 25 mg | $36.00 $143.00 $235.00 $541.00 | 1 | |
Acting as a selective GPR55 agonist, Abnormal cannabidiol promotes the activation of the receptor, inducing signaling pathways such as the β-arrestin pathway. | ||||||
Anandamide | 94421-68-8 | sc-396321 sc-396321A sc-396321B sc-396321C | 5 mg 25 mg 500 mg 1 g | $79.00 $215.00 $3988.00 $7660.00 | 2 | |
Anandamide acts as an endogenous ligand for GPR55, engaging in specific molecular interactions that activate distinct signaling cascades. Its unique structure allows for versatile binding, influencing receptor conformation and promoting varied intracellular responses. Anandamide's rapid degradation by fatty acid amide hydrolase (FAAH) ensures transient signaling, while its lipid-like properties facilitate integration into cellular membranes, enhancing its role in modulating synaptic plasticity and neuronal communication. | ||||||
Palmitoyl Ethanolamide-d4 | 1159908-45-8 | sc-224199 sc-224199A | 100 µg 500 µg | $29.00 $130.00 | ||
Palmitoyl Ethanolamide-d4 serves as a selective modulator of GPR55, exhibiting unique binding affinities that influence receptor dynamics. Its deuterated structure enhances stability and alters reaction kinetics, allowing for prolonged interaction with the receptor. This compound engages in specific lipid-mediated signaling pathways, promoting distinct cellular responses. Its hydrophobic characteristics facilitate membrane integration, impacting cellular communication and signaling efficiency. | ||||||
O-1602 | 317321-41-8 | sc-202745 sc-202745A | 1 mg 5 mg | $204.00 $408.00 | ||
A synthetic analog of cannabidiol, O-1602 acts as a selective agonist of GPR55, enhancing its functional activity by activating intracellular signaling pathways, including phospholipase C activation and calcium release. | ||||||
CAY10505 | 1218777-13-9 | sc-364456 sc-364456A | 10 mg 50 mg | $80.00 $280.00 | ||
GSK494581A acts as a GPR55 agonist, enhancing the receptor′s activity and leading to the activation of G protein-mediated signaling pathways. | ||||||
VPC 23019 | 449173-19-7 | sc-362817 | 10 mg | $357.00 | 4 | |
Although primarily an S1P receptor antagonist, VPC 23019 interacts with GPR55 and may enhance GPR55-mediated signaling pathways, especially those involved in cellular migration and immune response. | ||||||