GPR119 Activators
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Oleylethanolamide | 111-58-0 | sc-201400 sc-201400A | 10 mg 50 mg | $88.00 $190.00 | 1 | |
OEA is a bioactive lipid that directly activates GPR119. It binds to the receptor's orthosteric site, triggering a conformational change that activates intracellular signaling cascades, including the adenylate cyclase-cAMP pathway. | ||||||
PSN 375963 hydrochloride | 388575-52-8 | sc-204219 sc-204219A | 10 mg 50 mg | $175.00 $739.00 | ||
PSN 375963 hydrochloride functions as a GPR119 agonist, engaging in selective binding to the receptor's allosteric site. Its unique molecular architecture facilitates specific hydrophobic interactions and stabilizes receptor conformation, enhancing downstream signaling. The compound exhibits a favorable kinetic profile, characterized by a moderate binding affinity that allows for sustained receptor activation, thereby influencing metabolic pathways and cellular signaling dynamics effectively. | ||||||
AS 1269574 | 330981-72-1 | sc-361109 sc-361109A | 10 mg 50 mg | $155.00 $620.00 | ||
AS 1269574 acts as a GPR119 modulator, characterized by its ability to induce conformational changes in the receptor through unique electrostatic interactions. This compound's distinct structural features promote enhanced receptor dimerization, which is crucial for optimal signaling. Its reaction kinetics reveal a rapid onset of action, allowing for effective modulation of intracellular pathways. The compound's solubility profile further supports its dynamic interactions within biological systems. | ||||||
2-Oleoylglycerol | 3443-84-3 | sc-213888 sc-213888B sc-213888A | 1 mg 5 mg 10 mg | $52.00 $173.00 $316.00 | 2 | |
2-Oleoylglycerol functions as a GPR119 agonist, exhibiting a unique affinity for the receptor that facilitates specific ligand-receptor interactions. Its hydrophobic tail enhances membrane integration, promoting receptor activation through allosteric modulation. The compound's kinetic profile indicates a sustained engagement with GPR119, leading to prolonged signaling effects. Additionally, its lipid-like properties contribute to its ability to traverse cellular membranes efficiently, influencing metabolic pathways. | ||||||
Sodium oleate | 143-19-1 | sc-215879 sc-215879A | 250 mg 1 g | $45.00 $100.00 | 3 | |
Sodium oleate, a salt of oleic acid, can be metabolized to OEA, which directly activates GPR119. This increases cAMP levels and leads to enhanced insulin secretion. | ||||||
Linoleic Acid | 60-33-3 | sc-200788 sc-200788A sc-200788B sc-200788C | 100 mg 1 g 5 g 25 g | $33.00 $63.00 $163.00 $275.00 | 4 | |
Sodium linoleate, a salt of linoleic acid, can be metabolized to linoleoylethanolamide (LEA), which can activate GPR119, leading to increased cAMP levels and enhanced insulin secretion. | ||||||
Sodium palmitate | 408-35-5 | sc-215881 sc-215881A sc-215881B sc-215881C | 5 g 10 g 25 g 500 g | $105.00 $195.00 $260.00 $2100.00 | 6 | |
Sodium palmitate, a salt of palmitic acid, can be metabolized to palmitoylethanolamide (PEA), which can activate GPR119, leading to increased cAMP levels and enhanced insulin secretion. | ||||||
Sodium stearate | 822-16-2 | sc-215884 sc-215884A | 1 g 5 g | $41.00 $102.00 | 1 | |
Sodium stearate, a salt of stearic acid, can be metabolized to stearoylethanolamide (SEA), which can activate GPR119, leading to increased cAMP levels and enhanced insulin secretion. | ||||||
1,2-Dioctanoyl-sn-glycerol | 60514-48-9 | sc-202397 sc-202397A | 10 mg 50 mg | $46.00 $249.00 | 2 | |
Diacylglycerol can be metabolized to various N-acylethanolamines that can activate GPR119, leading to increased cAMP levels and enhanced insulin secretion. | ||||||
Palmitic Acid | 57-10-3 | sc-203175 sc-203175A | 25 g 100 g | $112.00 $280.00 | 2 | |
Palmitic acid can be metabolized to palmitoylethanolamide (PEA), which can activate GPR119, leading to increased cAMP levels and enhanced insulin secretion. | ||||||