GPR1 Activators
GPR1, as a G protein-coupled receptor, is integral to numerous cellular signaling pathways. Its activation is influenced by the balance and interaction of various extracellular signals and intracellular messengers. Compounds like Forskolin and Isoproterenol, which enhance the production of cAMP, a key secondary messenger in G protein-coupled receptor signaling, can potentially enhance GPR1 activity. The increase in cAMP levels leads to the activation of protein kinase A (PKA), which can influence various signaling pathways associated with GPR1.
Additionally, substances like IBMX that inhibit the degradation of cAMP, along with neurotransmitters and hormones such as Epinephrine, Dopamine, Histamine, Serotonin, Acetylcholine, Adenosine, Glucagon, and Oxytocin, can modulate GPR1 activity indirectly. These compounds interact with their respective G protein-coupled receptors and can influence the signaling pathways in which GPR1 is involved. For instance, Prostaglandin E2, known for its role in inflammatory responses, could also affect GPR1 activity through related G protein-coupled receptor signaling.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Activates adenylyl cyclase, increasing cAMP levels and potentially enhancing GPR1 signaling. | ||||||
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $28.00 $38.00 | 5 | |
A beta-adrenergic agonist that can increase cAMP, potentially enhancing GPR1-mediated signaling. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $260.00 $350.00 $500.00 | 34 | |
A non-selective inhibitor of phosphodiesterases, increases cAMP levels, potentially enhancing GPR1 activity. | ||||||
(−)-Epinephrine | 51-43-4 | sc-205674 sc-205674A sc-205674B sc-205674C sc-205674D | 1 g 5 g 10 g 100 g 1 kg | $41.00 $104.00 $201.00 $1774.00 $16500.00 | ||
A natural ligand for adrenergic receptors, could enhance GPR1 signaling indirectly through cAMP pathway modulation. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $57.00 $159.00 $275.00 $678.00 | 37 | |
Can activate G protein-coupled receptors, potentially influencing GPR1 signaling pathways. | ||||||
Dopamine | 51-61-6 | sc-507336 | 1 g | $290.00 | ||
As a neurotransmitter, can modulate GPR1 activity indirectly through dopaminergic pathways. | ||||||
Histamine, free base | 51-45-6 | sc-204000 sc-204000A sc-204000B | 1 g 5 g 25 g | $94.00 $283.00 $988.00 | 7 | |
Activates G protein-coupled histamine receptors, potentially modulating GPR1 activity. | ||||||
Serotonin hydrochloride | 153-98-0 | sc-201146 sc-201146A | 100 mg 1 g | $118.00 $187.00 | 15 | |
Influences GPR1 activity indirectly through serotonin receptor-mediated pathways. | ||||||
Adenosine | 58-61-7 | sc-291838 sc-291838A sc-291838B sc-291838C sc-291838D sc-291838E sc-291838F | 1 g 5 g 100 g 250 g 1 kg 5 kg 10 kg | $34.00 $48.00 $300.00 $572.00 $1040.00 $2601.00 $4682.00 | 1 | |
Activates adenosine receptors, potentially influencing GPR1 signaling pathways. | ||||||
Oxytocin acetate salt | 50-56-6 | sc-279938 sc-279938A sc-279938B sc-279938C sc-279938D sc-279938E | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $60.00 $180.00 $337.00 $663.00 $969.00 $1836.00 | 4 | |
As a hormone and neurotransmitter, could modulate GPR1 activity through G protein-coupled receptor pathways. | ||||||