GPI Inhibitors
Items 1 to 10 of 13 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $65.00 $210.00 | 26 | |
2-Deoxy-D-glucose (CAS 154-17-6) is a chemical compound that acts as an inhibitor of glycosylphosphatidylinositol (GPI) anchors. It interferes with the biosynthesis of GPI anchors, which are essential lipid moieties that attach specific proteins to the cell membrane. By inhibiting GPI anchor biosynthesis, 2-deoxy-D-glucose disrupts the attachment of GPI-anchored proteins to the cell membrane, potentially impacting various cellular processes that rely on GPI anchors. | ||||||
Propranolol | 525-66-6 | sc-507425 | 100 mg | $180.00 | ||
Propranolol, a nonselective beta-adrenergic antagonist, can inhibit the activation of adenylyl cyclase, reducing cAMP levels and thereby influencing GPI-anchor biosynthesis | ||||||
Geneticin (G418) Sulfate | 108321-42-2 | sc-29065 sc-29065A sc-29065C sc-29065D sc-29065B | 1 g 5 g 100 g 500 g 25 g | $106.00 $381.00 $1500.00 $6125.00 $459.00 | 193 | |
G418 is an aminoglycoside antibiotic that has been shown to inhibit GPI anchor biosynthesis, affecting the attachment of certain proteins to the cell membrane. | ||||||
Manumycin A | 52665-74-4 | sc-200857 sc-200857A | 1 mg 5 mg | $215.00 $622.00 | 5 | |
Manumycin A is a farnesyltransferase inhibitor that can suppress the prenylation of proteins, a crucial step in GPI-anchor biosynthesis | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $169.00 $299.00 | 66 | |
Tunicamycin inhibits N-acetylglucosamine transferase, a key enzyme involved in the early steps of GPI-anchor biosynthesis | ||||||
Cholesterol | 57-88-5 | sc-202539C sc-202539E sc-202539A sc-202539B sc-202539D sc-202539 | 5 g 5 kg 100 g 250 g 1 kg 25 g | $26.00 $2754.00 $126.00 $206.00 $572.00 $86.00 | 11 | |
Cholesterol can modulate the fluidity and integrity of lipid rafts, which are crucial for GPI-anchored proteins' function | ||||||
Methyl-β-cyclodextrin | 128446-36-6 | sc-215379A sc-215379 sc-215379C sc-215379B | 100 mg 1 g 10 g 5 g | $25.00 $65.00 $170.00 $110.00 | 19 | |
Methyl-β-cyclodextrin can extract cholesterol from the plasma membrane, potentially disrupting GPI-anchor localization | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD98059 is a MEK inhibitor that can suppress the MAPK pathway, a signaling cascade that can affect the function of GPI-anchored proteins | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a PI3K inhibitor that can suppress the PI3K-Akt pathway, a signaling cascade that can influence the function of GPI-anchored proteins | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin is another PI3K inhibitor that can also suppress the PI3K-Akt pathway, possibly affecting the function of GPI-anchored proteins | ||||||