GPD2 Activators encompass a diverse group of compounds that influence GPD2's activity through modulation of cellular metabolic pathways, particularly those related to lipid metabolism and energy production. These activators do not interact directly with GPD2; instead, they exert their influence through their roles in various biochemical pathways. For instance, compounds like Acetyl-CoA and Citrate, integral to the lipid synthesis pathway, modify the lipid environment in which GPD2 operates, thereby modulating its activity. Similarly, intermediates of the citric acid cycle, such as Malate, Oxaloacetate, and Succinate, impact GPD2 indirectly by influencing the cellular redox state and energy balance. This modulation of the redox state is crucial, as GPD2's activity is closely tied to the cellular energy status.
Additionally, compounds like NAD+ and Coenzyme Q10, pivotal in energy metabolism, also play a significant role. By altering the NADH/NAD+ and NADPH/NADP+ ratios, these compounds indirectly regulate GPD2 activity. This regulation is crucial for maintaining a balance between lipid synthesis and degradation, reflecting GPD2's role in these processes. Furthermore, L-Carnitine's facilitation of fatty acid transport into mitochondria for beta-oxidation exemplifies another mechanism by which GPD2 activity can be indirectly modulated. The intricate interplay of these compounds within various metabolic pathways highlights the complex regulation of GPD2 activity.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Acetyl coenzyme A trisodium salt | 102029-73-2 | sc-210745 sc-210745A sc-210745B | 1 mg 5 mg 1 g | $46.00 $80.00 $5712.00 | 3 | |
Acetyl-CoA is a key molecule in metabolism, involved in several pathways including lipid synthesis. It can influence GPD2 indirectly by contributing to the lipid environment that GPD2 acts upon, thereby modulating its activity. | ||||||
NAD+, Free Acid | 53-84-9 | sc-208084B sc-208084 sc-208084A sc-208084C sc-208084D sc-208084E sc-208084F | 1 g 5 g 10 g 25 g 100 g 1 kg 5 kg | $56.00 $186.00 $296.00 $655.00 $2550.00 $3500.00 $10500.00 | 4 | |
Nicotinamide adenine dinucleotide (NAD+) is a coenzyme found in all living cells. It's essential for energy metabolism and can indirectly affect GPD2 by altering the redox state and energy status of the cell. | ||||||
Malic acid | 6915-15-7 | sc-257687 | 100 g | $127.00 | 2 | |
Malate plays a role in the citric acid cycle, a key metabolic pathway. Its levels can impact the balance of NADH/NAD+ ratio, thus influencing GPD2 activity indirectly through changes in cellular energy balance. | ||||||
Oxaloacetic Acid | 328-42-7 | sc-279934 sc-279934A sc-279934B | 25 g 100 g 1 kg | $300.00 $944.00 $7824.00 | 1 | |
Oxaloacetate is a metabolite in the citric acid cycle and can influence GPD2 by affecting the availability of NADH and thus the redox state of the cell. | ||||||
Pyruvic acid | 127-17-3 | sc-208191 sc-208191A | 25 g 100 g | $40.00 $94.00 | ||
Pyruvate is a key intermediate in several metabolic pathways. It can influence GPD2 activity indirectly by affecting the overall metabolic flux and energy status of the cell. | ||||||
Citric Acid, Anhydrous | 77-92-9 | sc-211113 sc-211113A sc-211113B sc-211113C sc-211113D | 500 g 1 kg 5 kg 10 kg 25 kg | $49.00 $108.00 $142.00 $243.00 $586.00 | 1 | |
Citrate is a critical intermediate in the citric acid cycle. It can indirectly influence GPD2 activity by modulating the availability of acetyl-CoA and thus lipid metabolism. | ||||||
α-Ketoglutaric Acid | 328-50-7 | sc-208504 sc-208504A sc-208504B sc-208504C sc-208504D sc-208504E sc-208504F | 25 g 100 g 250 g 500 g 1 kg 5 kg 16 kg | $32.00 $42.00 $62.00 $108.00 $184.00 $724.00 $2050.00 | 2 | |
Alpha-ketoglutarate is involved in the citric acid cycle and amino acid metabolism. It can indirectly affect GPD2 by influencing cellular energy levels and redox state. | ||||||
Succinic acid | 110-15-6 | sc-212961B sc-212961 sc-212961A | 25 g 500 g 1 kg | $44.00 $74.00 $130.00 | ||
Succinate is a component of the citric acid cycle. Its levels can indirectly affect GPD2 activity by altering the cellular energy state and redox balance. | ||||||
Fumaric acid | 110-17-8 | sc-250031 sc-250031A sc-250031B sc-250031C | 25 g 100 g 500 g 2.5 kg | $42.00 $56.00 $112.00 $224.00 | ||
Fumarate, part of the citric acid cycle, can influence GPD2 activity indirectly by affecting the balance of cellular metabolites and energy status. | ||||||
L-Carnitine | 541-15-1 | sc-205727 sc-205727A sc-205727B sc-205727C | 1 g 5 g 100 g 250 g | $23.00 $33.00 $77.00 $175.00 | 3 | |
L-Carnitine plays a crucial role in the transport of fatty acids into mitochondria for beta-oxidation. It can indirectly influence GPD2 activity by modulating lipid metabolism and energy production. |