GOLT1A Activators
GOLT1A Activators belong to a distinct category of chemical compounds or molecules designed or identified with the specific intent of modulating the activity of the GOLT1A gene. GOLT1A, or Golgi Transport 1A, is a protein-coding gene found in humans and other organisms. It plays a crucial role in intracellular trafficking, particularly within the Golgi apparatus, a cellular organelle responsible for protein processing, modification, and sorting.
The study of GOLT1A activators is of significant interest because it offers researchers the opportunity to investigate the gene's precise involvement in cellular physiology and molecular mechanisms related to intracellular transport and Golgi function. Activation of GOLT1A can provide valuable insights into its potential roles in processes such as protein trafficking, glycosylation, and cargo sorting within the Golgi apparatus. By manipulating the activity of GOLT1A through these activators, scientists aim to gain a deeper understanding of the complex molecular pathways and cellular functions that rely on the gene product, thereby contributing to the broader knowledge of intracellular trafficking and Golgi biology. Consequently, GOLT1A activators serve as essential tools for researchers dedicated to unraveling the intricate molecular mechanisms that govern cellular biology, particularly within the context of Golgi-related processes and protein transport.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $30.00 $52.00 $122.00 $367.00 | 25 | |
Brefeldin A disrupts Golgi structure and function, which could trigger a compensatory upregulation of related genes like GOLT1A. | ||||||
Monensin A | 17090-79-8 | sc-362032 sc-362032A | 5 mg 25 mg | $152.00 $515.00 | ||
Monensin alters Golgi apparatus function, potentially influencing the expression of genes involved in Golgi trafficking. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $58.00 $83.00 $140.00 $242.00 | 38 | |
Nocodazole disrupts microtubule dynamics, which might initiate cellular responses that increase GOLT1A expression for maintaining transport. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $40.00 $73.00 $217.00 $242.00 $724.00 $1196.00 | 39 | |
Paclitaxel stabilizes microtubules and could affect intracellular transport, possibly altering GOLT1A expression. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin raises intracellular cAMP levels, which may lead to changes in gene expression profiles, including GOLT1A. | ||||||
17-AAG | 75747-14-7 | sc-200641 sc-200641A | 1 mg 5 mg | $66.00 $153.00 | 16 | |
17-AAG affects protein folding and could upregulate genes associated with protein trafficking due to cellular stress responses. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
MG132 inhibits proteasome activity, potentially leading to an increase in the expression of proteins involved in cellular transport. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $68.00 | 2 | |
Chloroquine impacts endosomal and lysosomal function, which might secondarily influence the expression of Golgi-related genes. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
Thapsigargin disrupts calcium homeostasis in the ER, which could affect the expression of genes related to intracellular transport. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $169.00 $299.00 | 66 | |
Tunicamycin inhibits N-linked glycosylation, which may trigger a cellular response to upregulate genes like GOLT1A. | ||||||