Gm5849 Inhibitors
Gm5849 inhibitors are a class of chemical compounds specifically designed to target and inhibit the function of the Gm5849 gene, which is not yet fully characterized but is believed to play a role in important cellular processes. Genes like Gm5849 are often involved in regulating various aspects of gene expression, cellular signaling, or protein interactions. While the precise functions of Gm5849 remain unclear, it is likely that this gene influences processes such as transcriptional regulation, cellular differentiation, or intracellular communication. Inhibiting Gm5849 provides researchers with an opportunity to explore its specific contributions to these cellular mechanisms, shedding light on how it might participate in maintaining normal cellular homeostasis or in the regulation of gene expression networks that govern essential biological functions.
In research settings, Gm5849 inhibitors serve as important tools for investigating the molecular pathways in which Gm5849 is involved. By blocking Gm5849 activity, scientists can study how its inhibition affects downstream cellular processes, such as the alteration of gene expression profiles, disruptions in protein-protein interactions, or changes in signaling pathways that are critical for cellular function. This inhibition allows for detailed exploration of how Gm5849 interacts with other cellular components and how it contributes to processes such as cell growth, differentiation, and the response to environmental stimuli. Additionally, Gm5849 inhibitors provide insights into the broader regulatory networks that maintain cellular balance and coordination, helping researchers better understand the complex interplay of genes and proteins in maintaining normal cellular physiology. Through these studies, the use of Gm5849 inhibitors enhances our knowledge of gene regulation and cellular dynamics, particularly in the context of genes that are not yet fully understood.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
BAPTA/AM | 126150-97-8 | sc-202488 sc-202488A | 25 mg 100 mg | $138.00 $449.00 | 61 | |
Cell-permeable calcium chelator. BAPTA-AM inhibits Gm5849 indirectly by sequestering cytoplasmic calcium ions, disrupting calcium ion binding activity. This interference negatively impacts calcium-dependent protein binding activity, essential for Gm5849 function in processes like autocrine signaling, leukocyte migration, and neutrophil aggregation. | ||||||
Ruthenium red | 11103-72-3 | sc-202328 sc-202328A | 500 mg 1 g | $184.00 $245.00 | 13 | |
Calcium ion channel blocker. Ruthenium Red inhibits Gm5849 indirectly by preventing the influx of extracellular calcium ions, disrupting calcium ion binding activity. This inhibition negatively affects calcium-dependent protein binding, impeding Gm5849's involvement in autocrine signaling, leukocyte migration, and neutrophil aggregation. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
Sarco/endoplasmic reticulum calcium ATPase (SERCA) inhibitor. Thapsigargin inhibits Gm5849 indirectly by disrupting calcium homeostasis in the endoplasmic reticulum. This disturbance impairs calcium ion binding and calcium-dependent protein interactions, influencing Gm5849's role in autocrine signaling, leukocyte migration, and neutrophil aggregation. | ||||||
Nifedipine | 21829-25-4 | sc-3589 sc-3589A | 1 g 5 g | $58.00 $170.00 | 15 | |
L-type calcium channel blocker. Nifedipine inhibits Gm5849 indirectly by preventing calcium influx through L-type channels, impacting calcium ion binding activity. This disruption negatively influences calcium-dependent protein interactions, hindering Gm5849's involvement in autocrine signaling, leukocyte migration, and neutrophil aggregation. | ||||||
TMB-8 • HCl | 53464-72-5 | sc-3522 sc-3522A | 10 mg 50 mg | $42.00 $126.00 | 10 | |
Intracellular calcium release inhibitor. TMB-8 inhibits Gm5849 indirectly by suppressing the release of calcium from intracellular stores. This interference disrupts calcium ion binding and calcium-dependent protein interactions, affecting Gm5849's participation in autocrine signaling, leukocyte migration, and neutrophil aggregation. | ||||||
SK&F 96365 | 130495-35-1 | sc-201475 sc-201475B sc-201475A sc-201475C | 5 mg 10 mg 25 mg 50 mg | $101.00 $155.00 $389.00 $643.00 | 2 | |
Calcium channel blocker and store-operated calcium entry (SOCE) inhibitor. SKF-96365 inhibits Gm5849 indirectly by preventing calcium entry through store-operated channels, impairing calcium ion binding activity. This disruption negatively influences calcium-dependent protein interactions, hindering Gm5849's role in autocrine signaling, leukocyte migration, and neutrophil aggregation. | ||||||
Ryanodine | 15662-33-6 | sc-201523 sc-201523A | 1 mg 5 mg | $219.00 $765.00 | 19 | |
Ryanodine receptor antagonist. Ryanodine inhibits Gm5849 indirectly by blocking calcium release from the endoplasmic reticulum through ryanodine receptors. This interference disrupts calcium ion binding and calcium-dependent protein interactions, impacting Gm5849's participation in autocrine signaling, leukocyte migration, and neutrophil aggregation. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $54.00 $128.00 $199.00 $311.00 | 23 | |
Ionophore facilitating calcium ion transport. Calcimycin inhibits Gm5849 indirectly by elevating cytoplasmic calcium levels, disrupting calcium ion binding activity. This interference negatively impacts calcium-dependent protein interactions, impairing Gm5849's involvement in autocrine signaling, leukocyte migration, and neutrophil aggregation. | ||||||
EGTA | 67-42-5 | sc-3593 sc-3593A sc-3593B sc-3593C sc-3593D | 1 g 10 g 100 g 250 g 1 kg | $20.00 $62.00 $116.00 $246.00 $799.00 | 23 | |
Calcium chelator. EGTA inhibits Gm5849 indirectly by sequestering extracellular calcium ions, disrupting calcium ion binding activity. This interference negatively influences calcium-dependent protein interactions, hindering Gm5849's role in autocrine signaling, leukocyte migration, and neutrophil aggregation. | ||||||
2-APB | 524-95-8 | sc-201487 sc-201487A | 20 mg 100 mg | $27.00 $52.00 | 37 | |
Inositol trisphosphate receptor (IP3R) and transient receptor potential (TRP) channel inhibitor. 2-APB inhibits Gm5849 indirectly by modulating intracellular calcium release, disrupting calcium ion binding activity. This interference negatively impacts calcium-dependent protein interactions, impairing Gm5849's involvement in autocrine signaling, leukocyte migration, and neutrophil aggregation. | ||||||