Date published: 2026-4-1

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Gm1305 Inhibitors

GM1305 inhibitors represent a class of chemical compounds specifically designed to interfere with the function of the protein GM1305, which is known to be involved in cellular processes such as cell migration, intracellular signaling, and cellular architecture regulation. The structural characteristics of these inhibitors are diverse but typically involve motifs that enable high-affinity binding to the GM1305 protein or its associated complexes. These inhibitors can exhibit a variety of chemical backbones, such as heterocyclic scaffolds, aromatic rings, and substituted aliphatic chains, which contribute to their selective binding and modulating activity. The binding interaction is often facilitated by hydrogen bonding, hydrophobic contacts, and, in some cases, covalent attachment to specific active site residues of GM1305. By targeting key functional domains of GM1305, these inhibitors are able to disrupt its interactions with other cellular proteins and affect its normal role in cellular signaling pathways.

On a molecular level, GM1305 inhibitors often function by altering the protein's conformation or blocking specific domains crucial for its activity, thus preventing GM1305 from executing its cellular roles. Such inhibitors may be designed with specificity in mind to reduce off-target effects and unintended cellular interactions. Depending on their design, these compounds may have variable selectivity for different isoforms or homologs of GM1305, which can influence their potency and efficacy in biological studies. The chemical optimization of these inhibitors typically involves balancing their solubility, stability, and cellular permeability to enhance their performance in biological systems. Furthermore, studies of these inhibitors help elucidate the precise functional roles of GM1305 in cellular processes, providing valuable insights into its mechanisms of action and the broader biological pathways in which it plays a role. Overall, GM1305 inhibitors serve as important molecular tools in biochemical research for probing the functions and interactions of the GM1305 protein within cells.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Taxol

33069-62-4sc-201439D
sc-201439
sc-201439A
sc-201439E
sc-201439B
sc-201439C
1 mg
5 mg
25 mg
100 mg
250 mg
1 g
$41.00
$74.00
$221.00
$247.00
$738.00
$1220.00
39
(2)

Stabilizes microtubules and prevents their disassembly, thereby inhibiting microtubule motor proteins from walking along the microtubule track.

Colchicine

64-86-8sc-203005
sc-203005A
sc-203005B
sc-203005C
sc-203005D
sc-203005E
1 g
5 g
50 g
100 g
500 g
1 kg
$100.00
$321.00
$2289.00
$4484.00
$18207.00
$34749.00
3
(2)

Binds to tubulin and inhibits its polymerization, leading to the disruption of microtubule formation and function, affecting microtubule motor activity.

Nocodazole

31430-18-9sc-3518B
sc-3518
sc-3518C
sc-3518A
5 mg
10 mg
25 mg
50 mg
$59.00
$85.00
$143.00
$247.00
38
(2)

Depolymerizes microtubules and prevents their assembly, thereby inhibiting microtubule-associated motor protein functions.

Vinblastine

865-21-4sc-491749
sc-491749A
sc-491749B
sc-491749C
sc-491749D
10 mg
50 mg
100 mg
500 mg
1 g
$102.00
$235.00
$459.00
$1749.00
$2958.00
4
(0)

Binds to tubulin and inhibits microtubule assembly, which can interfere with microtubule motor proteins like kinesins.

Eribulin

253128-41-5sc-507547
5 mg
$865.00
(0)

Inhibits the growth phase of microtubule dynamics, affecting the function of microtubule motors by preventing proper microtubule formation.

Griseofulvin

126-07-8sc-202171A
sc-202171
sc-202171B
5 mg
25 mg
100 mg
$85.00
$220.00
$598.00
4
(2)

Disrupts microtubule function by binding to tubulin, potentially affecting microtubule motor proteins by altering microtubule polymer dynamics.

Podophyllotoxin

518-28-5sc-204853
100 mg
$84.00
1
(1)

Inhibits tubulin polymerization, leading to the alteration of microtubule dynamics and potential inhibition of microtubule-based motor protein activities.

Thiabendazole

148-79-8sc-204913
sc-204913A
sc-204913B
sc-204913C
sc-204913D
10 g
100 g
250 g
500 g
1 kg
$32.00
$84.00
$183.00
$312.00
$572.00
5
(1)

Binds to tubulin and inhibits its polymerization, potentially affecting the action of microtubule motor proteins.

2-Methoxyestradiol

362-07-2sc-201371
sc-201371A
10 mg
50 mg
$71.00
$288.00
6
(1)

Destabilizes microtubules and has been shown to inhibit microtubule motor proteins indirectly by affecting microtubule dynamics.

Monastrol

254753-54-3sc-202710
sc-202710A
1 mg
5 mg
$120.00
$233.00
10
(1)

Specifically inhibits the motor activity of the kinesin Eg5, which may suggest potential for inhibiting similar kinesin motor proteins.