Date published: 2025-11-24

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Glut6 Inhibitors

Glut6 inhibitors belong to a specialized category of chemical compounds that have attracted attention in the field of molecular biology and cellular glucose transport research. Glut6, or Glucose transporter 6, is a member of the glucose transporter protein family responsible for facilitating the transport of glucose across cell membranes. The term Glut6 inhibitors refers to a group of molecules meticulously designed to selectively target and modulate the activity of Glut6. These inhibitors serve as invaluable tools in laboratory investigations, enabling researchers to explore the intricate molecular functions and cellular processes associated with Glut6.

Glut6 inhibitors typically function by interfering with the transport function or expression of Glut6, potentially disrupting glucose uptake by cells that rely on this transporter. This interference can lead to alterations in cellular glucose metabolism, impacting various aspects of energy homeostasis and cellular processes that depend on glucose availability. Researchers employ Glut6 inhibitors to gain insights into the physiological roles and molecular interactions of Glut6 within cells, aiming to advance our understanding of the fundamental mechanisms involved in glucose transport, glucose sensing, and the regulation of glucose metabolism. Through the study of Glut6 inhibitors, scientists seek to unravel the complexities of cellular glucose utilization, glucose transport regulation, and the broader field of molecular and cellular biology, contributing to our knowledge of how cells manage glucose as a vital energy source.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$73.00
$238.00
$717.00
$2522.00
$21420.00
53
(3)

Actinomycin D binds to DNA and inhibits RNA polymerase, which can decrease the transcription of various genes, including those encoding transporters like GLUT6.

Triptolide

38748-32-2sc-200122
sc-200122A
1 mg
5 mg
$88.00
$200.00
13
(1)

Triptolide has been shown to inhibit the transcription of a wide range of genes, potentially affecting GLUT6 expression indirectly.

α-Amanitin

23109-05-9sc-202440
sc-202440A
1 mg
5 mg
$260.00
$1029.00
26
(2)

α-Amanitin targets RNA polymerase II and inhibits mRNA synthesis which could downregulate GLUT6 expression.

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

5-Azacytidine is a DNA methyltransferase inhibitor that can alter gene expression patterns, possibly affecting GLUT6 transcription.

Mithramycin A

18378-89-7sc-200909
1 mg
$54.00
6
(1)

Mithramycin A binds to DNA and affects transcription factor binding, potentially decreasing GLUT6 gene expression.

5-Aza-2′-Deoxycytidine

2353-33-5sc-202424
sc-202424A
sc-202424B
25 mg
100 mg
250 mg
$214.00
$316.00
$418.00
7
(1)

Decitabine is another DNA methyltransferase inhibitor, potentially altering the epigenetic state of the GLUT6 gene and its expression.

Chloroquine

54-05-7sc-507304
250 mg
$68.00
2
(0)

Chloroquine can elevate lysosomal pH and may disrupt transcriptional regulation, potentially affecting GLUT6 expression.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$62.00
$155.00
$320.00
233
(4)

Sirolimus inhibits mTOR, a pathway that controls protein synthesis at the translational level, which could indirectly reduce GLUT6 levels.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$42.00
$72.00
$124.00
$238.00
$520.00
$1234.00
11
(1)

Epigallocatechin gallate has been shown to alter gene expression profiles, which could theoretically reduce GLUT6 expression.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$60.00
$185.00
$365.00
64
(2)

Resveratrol influences various signaling pathways and gene expressions, which might affect GLUT6 expression.