GLT6D1 Activators
Forskolin and IBMX operate through the cAMP pathway, enhancing protein kinase A activity, which can lead to changes in the phosphorylation state of proteins associated with GLT6D1. PMA and ionomycin act by activating PKC and increasing intracellular calcium levels, respectively, both of which can lead to the modulation of proteins that interact with or regulate GLT6D1.
LY294002 and SF1670 engage with the PI3K/Akt pathway, a well-established signaling cascade that can regulate a multitude of cellular functions and protein activities, including GLT6D1. The MEK inhibitors PD98059 and U0126 exert their influence on the MAPK/ERK pathway, which is intricately involved in cell signaling and could affect the phosphorylation patterns of proteins that modulate GLT6D1. Rapamycin's interaction with the mTOR pathway can alter a broad array of cellular processes that have the potential to influence GLT6D1 activity. SC79 specifically targets Akt, enhancing its activity, which could lead to downstream effects on GLT6D1. A23187, like ionomycin, can increase intracellular calcium, which is a key regulator of numerous cellular functions, and therefore, could regulate GLT6D1. Piceatannol's inhibition of Syk kinase can alter signaling events, potentially leading to modulation of GLT6D1 activity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $260.00 $350.00 $500.00 | 34 | |
Non-specific inhibitor of phosphodiesterases, maintains increased levels of cAMP that can indirectly upregulate GLT6D1. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
Activates protein kinase C (PKC) which can phosphorylate proteins in pathways that regulate GLT6D1. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $78.00 $270.00 | 80 | |
Increases intracellular calcium concentration, potentially activating calcium-dependent proteins that interact with GLT6D1. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
Inhibits PI3K, altering downstream signaling that can result in the modulation of GLT6D1 activity. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
Inhibits MEK, which may alter ERK pathway signaling and consequently affect GLT6D1 activity. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $64.00 $246.00 | 136 | |
Inhibits MEK1/2, potentially modulating the MAPK/ERK pathway and influencing GLT6D1 activity. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Inhibits mTOR, which can lead to changes in cellular processes that regulate GLT6D1. | ||||||
2-Amino-6-chloro-α-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-acetic Acid Ethyl Ester | 305834-79-1 | sc-479756 | 25 mg | $380.00 | ||
Akt activator, can upregulate pathways leading to modulation of GLT6D1 activity. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $55.00 $131.00 $203.00 $317.00 | 23 | |
Ionophore that increases intracellular calcium, which can activate proteins that affect GLT6D1. | ||||||
Piceatannol | 10083-24-6 | sc-200610 sc-200610A sc-200610B | 1 mg 5 mg 25 mg | $51.00 $71.00 $199.00 | 11 | |
Inhibits Syk kinase, leading to altered signal transduction pathways that can affect GLT6D1. | ||||||