GAP1m Activators
GAP1m activators, as a category, encompass a range of chemical compounds known to stimulate, directly or indirectly, the activity of the GAP1m protein. This protein, crucial in nitrogen metabolism, can be influenced by alterations in the broader nitrogen metabolism network. When key nodes of this metabolic pathway are affected by chemicals, there is an increased reliance on transporters like GAP1m. The chemicals listed above either play roles in amino acid metabolism, nitrogen balance, or cellular osmolarity - each having their unique method of emphasizing the necessity of GAP1m.
These chemicals, by their very nature, do not act directly on GAP1m. Instead, they modulate the broader cellular environment or specific metabolic pathways that, in turn, render GAP1m more vital for maintaining cellular homeostasis. For instance, compounds like Alpha-Ketoglutarate or Urea, known to influence the Krebs cycle and nitrogen metabolism, respectively, exemplify how changes in primary metabolic pathways can indirectly necessitate increased activity of transporters like GAP1m. Thus, understanding these activators, especially in a detailed biochemical context, can provide insights into GAP1m's role and regulation in various cellular conditions.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
α-Ketoglutaric Acid | 328-50-7 | sc-208504 sc-208504A sc-208504B sc-208504C sc-208504D sc-208504E sc-208504F | 25 g 100 g 250 g 500 g 1 kg 5 kg 16 kg | $32.00 $42.00 $62.00 $108.00 $184.00 $724.00 $2050.00 | 2 | |
Alpha-ketoglutarate is involved in the Krebs cycle. Its presence can increase the requirement for amino acid transport, potentially highlighting the importance of GAP1m in amino acid uptake. | ||||||
Urea | 57-13-6 | sc-29114 sc-29114A sc-29114B | 1 kg 2 kg 5 kg | $30.00 $42.00 $76.00 | 17 | |
Urea's role as a non-preferred nitrogen source can stimulate the upregulation of GAP1m to increase uptake of alternative nitrogen sources. | ||||||
Azaserine | 115-02-6 | sc-29063 sc-29063A | 50 mg 250 mg | $306.00 $906.00 | 15 | |
An inhibitor of glutamine synthetase, Azaserine affects nitrogen metabolism. By disrupting glutamate conversion, it may heighten the relevance of amino acid uptake channels like GAP1m. | ||||||
L-Methionine [R,S]-Sulfoximine | 15985-39-4 | sc-207806 | 1 g | $388.00 | ||
MSX is an inhibitor of glutamine synthetase, thus impacting nitrogen metabolism. By impeding this pathway, it indirectly underscores GAP1m's role in making up for disruptions in nitrogen assimilation. | ||||||
Hydroxylamine solution | 7803-49-8 | sc-250136 | 100 ml | $71.00 | ||
As an inhibitor of various enzymatic reactions, hydroxylamine can disrupt normal nitrogen metabolism. This disruption could highlight the importance of transporters like GAP1m in compensating for changes in cellular nitrogen status. | ||||||
NOC-18 | 146724-94-9 | sc-202247 sc-202247A sc-202247B sc-202247C | 10 mg 50 mg 100 mg 500 mg | $50.00 $180.00 $299.00 $1100.00 | 18 | |
DETA-NO releases nitric oxide, which affects nitrogen balance in cells. Its presence might increase the necessity of transport channels like GAP1m in maintaining proper cellular nitrogen equilibrium. | ||||||
Phenylhydrazine | 100-63-0 | sc-250701 sc-250701A | 5 g 100 g | $44.00 $51.00 | ||
By affecting heme synthesis, Phenylhydrazine can influence cellular nitrogen status. This can indirectly stress the importance of GAP1m in maintaining nitrogen balance. | ||||||
L-NG-Nitroarginine Methyl Ester (L-NAME) | 51298-62-5 | sc-200333 sc-200333A sc-200333B | 1 g 5 g 25 g | $47.00 $105.00 $322.00 | 45 | |
An inhibitor of nitric oxide synthase, L-NAME impacts nitrogen metabolism. Its effects can make channels like GAP1m more relevant for cellular nitrogen balance. | ||||||
Meglumine | 6284-40-8 | sc-205383 sc-205383A sc-205383B sc-205383C | 50 g 250 g 500 g 1 kg | $50.00 $89.00 $140.00 $280.00 | ||
This compound affects cellular osmolarity. Changes in osmolarity can indirectly necessitate the role of transporters like GAP1m in amino acid uptake and nitrogen balance. | ||||||
Dimethyl Sulfoxide (DMSO) | 67-68-5 | sc-202581 sc-202581A sc-202581B | 100 ml 500 ml 4 L | $30.00 $115.00 $900.00 | 136 | |
DMSO, a common solvent, can affect cellular processes indirectly. Its impact on cellular metabolism could make transporters like GAP1m more essential. | ||||||