Date published: 2026-4-1

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Phenylhydrazine (CAS 100-63-0)

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Alternate Names:
Hydrazinobenzene; Monophenylhydrazine
Application:
Phenylhydrazine is An aryl hydrazine used in the investigation of oligosaccharides as well as the structure of photosystem II. It is also used in thepreparation of various dyes and pharmaceutical compounds. It.
CAS Number:
100-63-0
Purity:
≥97%
Molecular Weight:
108.14
Molecular Formula:
C6H8N2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Phenylhydrazine is a chemical reagent extensively used in synthetic chemistry for its ability to induce the formation of hydrazones, which are pivotal intermediates in the synthesis of various heterocyclic compounds. It acts as a nucleophile, reacting with carbonyl groups, particularly aldehydes and ketones. Additionally, researchers employ phenylhydrazine in the synthesis of azo dyes, utilizing its capacity to form azo bonds with electron-deficient species. In analytical chemistry, it is used in the qualitative determination of sugars, as it forms hydrazone derivatives that can be easily identified. Moreover, in the field of biochemistry, phenylhydrazine is a tool to study red blood cell metabolism, hemoglobin function, and the mechanisms of hemolysis.


Phenylhydrazine (CAS 100-63-0) References

  1. [Agaritine and phenylhydrazine derivatives in Agaricus bisporus and Agaricus blazei Murrill].  |  Akiyama, H. and Kondo, K. 2007. Shokuhin Eiseigaku Zasshi. 48: J397-401. PMID: 18203508
  2. Phenylhydrazine as a partial model for beta-thalassaemia red blood cell hemodynamic properties.  |  Ramot, Y., et al. 2008. Br J Haematol. 140: 692-700. PMID: 18302715
  3. Investigation on the chemiluminescence reaction of the phenylhydrazine-luminol-peroxide system.  |  Chandel, AL., et al. 2012. Luminescence. 27: 455-8. PMID: 22238221
  4. The oxidation of phenylhydrazine by tyrosinase.  |  Sung, YM., et al. 2013. Appl Biochem Biotechnol. 169: 2420-9. PMID: 23456281
  5. In situ observation of ninhydrin and phenylhydrazine reaction in solution by FTIR.  |  Turhan, O. and Tezbaşaran, E. 2013. Spectrochim Acta A Mol Biomol Spectrosc. 113: 297-301. PMID: 23735209
  6. Sensitive quantitation of residual phenylhydrazine in antipyrine by LC-ICP-MS with iodo derivatization.  |  Harigaya, K., et al. 2014. Anal Sci. 30: 845-50. PMID: 25109648
  7. Hematopoietic Effect of Amaranthus cruentus Extract on Phenylhydrazine-Induced Toxicity in Rats.  |  Pandey, S., et al. 2016. J Diet Suppl. 13: 607-15. PMID: 27027824
  8. Optimization of phenylhydrazine induced hyperbilirubinemia in experimental rabbit.  |  Nawaz, H., et al. 2016. Exp Anim. 65: 363-372. PMID: 27210076
  9. Applicability of Phenylhydrazine Labeling for Structural Studies of Fucosylated N-Glycans.  |  Lattová, E., et al. 2019. Anal Chem. 91: 7985-7990. PMID: 31141660
  10. Novel carboxylated pyrroline-2-one derivatives bearing a phenylhydrazine moiety: Design, synthesis, antifungal evaluation and 3D-QSAR analysis.  |  Chen, M., et al. 2020. Bioorg Med Chem Lett. 30: 127519. PMID: 32860979
  11. Repro-protective role of royal jelly in phenylhydrazine-induced hemolytic anemia in male mice: Histopathological, embryological, and biochemical evidence.  |  Anbara, H., et al. 2022. Environ Toxicol. 37: 1124-1135. PMID: 35099105
  12. Phenylhydrazine-induced anaemia reduces subcutaneous white and brown adipose tissues in hypothalamic obese rats.  |  de Souza, DW., et al. 2022. Exp Physiol. 107: 575-588. PMID: 35396880
  13. Influence of phenylhydrazine on the antioxidant system of the erythrocytes and the liver in mice.  |  van Caneghem, P. 1984. Biochem Pharmacol. 33: 717-20. PMID: 6712704

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Phenylhydrazine, 5 g

sc-250701
5 g
$45.00

Phenylhydrazine, 100 g

sc-250701A
100 g
$52.00