γ Tubulin Inhibitors
γ Tubulin inhibitors comprise a group of chemicals that either directly or indirectly modulate the activity of γ Tubulin, a crucial protein involved in microtubule nucleation and organization. While there are limited direct inhibitors identified for γ Tubulin, several chemicals indirectly impact its function by influencing microtubule dynamics. Colchicine, Nocodazole, and Vinblastine are classic microtubule-targeting agents that indirectly affect γ Tubulin. These compounds bind to tubulin, disrupting microtubule polymerization and, consequently, influencing γ Tubulin-mediated microtubule nucleation. This disruption alters the microtubule network, impacting cellular processes reliant on γ Tubulin-regulated microtubule organization. Podophyllotoxin, Griseofulvin, and Thiabendazole are additional chemicals that indirectly affect γ Tubulin by inhibiting microtubule polymerization. Their impact on microtubule dynamics disrupts the microtubule network and influences cellular processes dependent on γ Tubulin-regulated microtubule organization.
Colcemid, ABT-751, and CA4P are compounds that inhibit microtubule polymerization, indirectly affecting γ Tubulin-mediated microtubule nucleation. Their influence on microtubule dynamics disrupts the microtubule network, impacting cellular processes reliant on γ Tubulin-regulated microtubule organization. Vinorelbine, Ansamitocin P-3, Griselimycin, and Peloruside A are additional chemicals that indirectly modulate γ Tubulin by affecting microtubule dynamics. Their actions lead to alterations in the microtubule network, influencing cellular processes dependent on γ Tubulin-regulated microtubule organization.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Colchicine | 64-86-8 | sc-203005 sc-203005A sc-203005B sc-203005C sc-203005D sc-203005E | 1 g 5 g 50 g 100 g 500 g 1 kg | $98.00 $315.00 $2244.00 $4396.00 $17850.00 $34068.00 | 3 | |
Colchicine disrupts microtubule polymerization by binding to tubulin, indirectly affecting γ Tubulin-mediated microtubule nucleation. This disruption alters the microtubule network, impacting cellular processes dependent on γ Tubulin-regulated microtubule organization. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $58.00 $83.00 $140.00 $242.00 | 38 | |
Nocodazole depolymerizes microtubules by binding to tubulin, indirectly affecting γ Tubulin-mediated microtubule nucleation. This depolymerization disrupts the microtubule network, influencing cellular processes reliant on γ Tubulin-regulated microtubule organization. | ||||||
Vinblastine | 865-21-4 | sc-491749 sc-491749A sc-491749B sc-491749C sc-491749D | 10 mg 50 mg 100 mg 500 mg 1 g | $100.00 $230.00 $450.00 $1715.00 $2900.00 | 4 | |
Vinblastine inhibits microtubule polymerization by binding to tubulin, indirectly impacting γ Tubulin-mediated microtubule nucleation. This inhibition disrupts the microtubule network, influencing cellular processes that rely on γ Tubulin-regulated microtubule organization. | ||||||
Podophyllotoxin | 518-28-5 | sc-204853 | 100 mg | $82.00 | 1 | |
Podophyllotoxin inhibits tubulin polymerization, indirectly affecting γ Tubulin-mediated microtubule nucleation. This inhibition alters the microtubule network, impacting cellular processes dependent on γ Tubulin-regulated microtubule organization. | ||||||
Griseofulvin | 126-07-8 | sc-202171A sc-202171 sc-202171B | 5 mg 25 mg 100 mg | $83.00 $216.00 $586.00 | 4 | |
Griseofulvin disrupts microtubule dynamics by binding to tubulin, indirectly influencing γ Tubulin-mediated microtubule nucleation. This disruption alters the microtubule network, impacting cellular processes reliant on γ Tubulin-regulated microtubule organization. | ||||||
Thiabendazole | 148-79-8 | sc-204913 sc-204913A sc-204913B sc-204913C sc-204913D | 10 g 100 g 250 g 500 g 1 kg | $31.00 $82.00 $179.00 $306.00 $561.00 | 5 | |
Thiabendazole inhibits microtubule polymerization, indirectly affecting γ Tubulin-mediated microtubule nucleation. This inhibition disrupts the microtubule network, influencing cellular processes that rely on γ Tubulin-regulated microtubule organization. | ||||||
Colcemid | 477-30-5 | sc-202550A sc-202550 sc-202550B sc-202550C sc-202550D sc-202550E | 1 mg 5 mg 10 mg 50 mg 100 mg 500 mg | $67.00 $159.00 $312.00 $928.00 $1856.00 $6706.00 | 7 | |
Colcemid inhibits microtubule polymerization by binding to tubulin, indirectly impacting γ Tubulin-mediated microtubule nucleation. This inhibition alters the microtubule network, influencing cellular processes dependent on γ Tubulin-regulated microtubule organization. | ||||||
ABT 751 | 141430-65-1 | sc-361097 sc-361097A | 10 mg 50 mg | $179.00 $825.00 | ||
ABT-751 inhibits microtubule polymerization, indirectly affecting γ Tubulin-mediated microtubule nucleation. This inhibition disrupts the microtubule network, impacting cellular processes reliant on γ Tubulin-regulated microtubule organization. | ||||||
Combrestatin A4 | 117048-59-6 | sc-204697 sc-204697A | 1 mg 5 mg | $45.00 $79.00 | ||
CA4P disrupts microtubule dynamics, indirectly influencing γ Tubulin-mediated microtubule nucleation. This disruption alters the microtubule network, impacting cellular processes dependent on γ Tubulin-regulated microtubule organization. | ||||||
Vinorelbine base | 71486-22-1 | sc-205885 sc-205885A sc-205885B sc-205885C sc-205885D | 1 mg 5 mg 25 mg 100 mg 1 g | $28.00 $79.00 $255.00 $775.00 $1938.00 | ||
Vinorelbine inhibits microtubule polymerization by binding to tubulin, indirectly affecting γ Tubulin-mediated microtubule nucleation. This inhibition disrupts the microtubule network, influencing cellular processes reliant on γ Tubulin-regulated microtubule organization. | ||||||