γ Tubulin Antibody (C-11): sc-17787
- γ Tubulin Antibody (C-11) is a mouse monoclonal IgG2a κ γ Tubulin antibody, cited in 97 publications, provided at 200 µg/ml
- raised against amino acids 269-451 of γ Tubulin of human origin
- gamma Tubulin Antibody (C-11) is recommended for detection of γ Tubulin of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-gamma Tubulin Antibody (C-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of γ Tubulin (C-11): sc-17787.
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for γ Tubulin Antibody (C-11) for WB and IHC(P) applications. These reagents are now offered in bundles with γ Tubulin Antibody (C-11) (see ordering information below).
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γ Tubulin Antibody (C-11) is a mouse monoclonal IgG2a kappa light chain antibody that detects gamma Tubulin protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). anti-gamma Tubulin antibody (C-11) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. gamma Tubulin plays a crucial role in microtubule organization and is essential for the formation of the microtubule cytoskeleton, which is vital for numerous cellular processes, including cell division, intracellular transport, and maintaining cell shape. gamma Tubulin serves as a key component of the gammasome, a complex that acts as a nucleation site for microtubule assembly at the centrosome, thereby facilitating proper organization of microtubules during mitosis. This function ensures accurate chromosome segregation and stability during cell division, which is critical for maintaining genomic integrity. gamma Tubulin interacts with other proteins such as delta and epsilon Tubulin, which are also associated with the centrosome, further highlighting gamma Tubulin′s integral role in the microtubule network and cellular architecture.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
γ Tubulin Antibody (C-11) References:
- Microtubule nucleation by γ-tubulin complexes. | Kollman, JM., et al. 2011. Nat Rev Mol Cell Biol. 12: 709-21. PMID: 21993292
- Regulation of microtubule nucleation mediated by γ-tubulin complexes. | Sulimenko, V., et al. 2017. Protoplasma. 254: 1187-1199. PMID: 28074286
- γ-tubulin as a signal-transducing molecule and meshwork with therapeutic potential. | Alvarado-Kristensson, M. 2018. Signal Transduct Target Ther. 3: 24. PMID: 30221013
- Microtubule nucleation by γ-tubulin complexes and beyond. | Tovey, CA. and Conduit, PT. 2018. Essays Biochem. 62: 765-780. PMID: 30315097
- γ-Tubulin⁻γ-Tubulin Interactions as the Basis for the Formation of a Meshwork. | Rosselló, CA., et al. 2018. Int J Mol Sci. 19: PMID: 30347727
- γ-Tubulin Complexes and Fibrillar Arrays: Two Conserved High Molecular Forms with Many Cellular Functions. | Chumová, J., et al. 2021. Cells. 10: PMID: 33915825
- CAMSAP2 organizes a γ-tubulin-independent microtubule nucleation centre through phase separation. | Imasaki, T., et al. 2022. Elife. 11: PMID: 35762204
- Multifaceted modes of γ-tubulin complex recruitment and microtubule nucleation at mitotic centrosomes. | Zhu, Z., et al. 2023. J Cell Biol. 222: PMID: 37698931
- Transition of human γ-tubulin ring complex into a closed conformation during microtubule nucleation. | Brito, C., et al. 2024. Science. 383: 870-876. PMID: 38305685
- Structure of the γ-tubulin ring complex-capped microtubule. | Aher, A., et al. 2024. Nat Struct Mol Biol. 31: 1124-1133. PMID: 38609661
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
γ Tubulin Antibody (C-11) | sc-17787 | 200 µg/ml | $316.00 | |||
γ Tubulin Antibody (C-11): m-IgG Fc BP-HRP Bundle | sc-528314 | 200 µg Ab; 10 µg BP | $354.00 | |||
γ Tubulin Antibody (C-11): m-IgGκ BP-HRP Bundle | sc-520658 | 200 µg Ab, 40 µg BP | $354.00 | |||
γ Tubulin Antibody (C-11): m-IgG2a BP-HRP Bundle | sc-547070 | 200 µg Ab; 10 µg BP | $354.00 | |||
γ Tubulin Antibody (C-11) AC | sc-17787 AC | 500 µg/ml, 25% agarose | $416.00 | |||
γ Tubulin Antibody (C-11) HRP | sc-17787 HRP | 200 µg/ml | $316.00 | |||
γ Tubulin Antibody (C-11) FITC | sc-17787 FITC | 200 µg/ml | $330.00 | |||
γ Tubulin Antibody (C-11) PE | sc-17787 PE | 200 µg/ml | $343.00 | |||
γ Tubulin Antibody (C-11) Alexa Fluor® 488 | sc-17787 AF488 | 200 µg/ml | $357.00 | |||
γ Tubulin Antibody (C-11) Alexa Fluor® 546 | sc-17787 AF546 | 200 µg/ml | $357.00 | |||
γ Tubulin Antibody (C-11) Alexa Fluor® 594 | sc-17787 AF594 | 200 µg/ml | $357.00 | |||
γ Tubulin Antibody (C-11) Alexa Fluor® 647 | sc-17787 AF647 | 200 µg/ml | $357.00 | |||
γ Tubulin Antibody (C-11) Alexa Fluor® 680 | sc-17787 AF680 | 200 µg/ml | $357.00 | |||
γ Tubulin Antibody (C-11) Alexa Fluor® 790 | sc-17787 AF790 | 200 µg/ml | $357.00 |