γ Tubulin Activators
γ Tubulin activators constitute a diverse class of compounds that influence the function of γ Tubulin, a critical regulator of microtubule nucleation and organization. These compounds exert their effects through direct or indirect modulation of microtubule dynamics, ultimately impacting the microtubule-organizing center where γ Tubulin plays a pivotal role. Nocodazole, Colchicine, and Vinblastine are microtubule destabilizers that indirectly affect γ Tubulin by disrupting microtubule assembly. These compounds bind to tubulin, leading to alterations in the microtubule-organizing center and influencing processes such as mitosis and intracellular transport. Conversely, microtubule-stabilizing agents like Paclitaxel and Docetaxel indirectly activate γ Tubulin by promoting microtubule assembly, resulting in stabilized microtubules and impacting cellular processes.
Additional compounds such as Griseofulvin, Podophyllotoxin, and Thiocolchicoside interfere with microtubule assembly, indirectly modulating γ Tubulin. Their binding to tubulin disrupts the microtubule-organizing center, leading to changes in γ Tubulin function and influencing cell division and intracellular transport. Moreover, Vinorelbine, Griselimycin, Vinflunine, and Albendazole showcase the diversity of γ Tubulin activators, each with unique mechanisms of action.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $40.00 $73.00 $217.00 $242.00 $724.00 $1196.00 | 39 | |
Paclitaxel, a microtubule-stabilizing agent, indirectly impacts γ Tubulin by promoting microtubule assembly. By binding to tubulin subunits, paclitaxel stabilizes microtubules, affecting the microtubule-organizing center where γ Tubulin is involved in microtubule nucleation. | ||||||
Vinflunine | 162652-95-1 | sc-507411 | 10 mg | $390.00 | ||
Vinflunine is a microtubule-targeting agent that indirectly impacts γ Tubulin by disrupting microtubule dynamics. It binds to tub ulin, inhibiting microtubule assembly and affecting the microtubule-organizing center where γ Tubulin is involved in microtubule nucleation. | ||||||
Albendazole | 54965-21-8 | sc-210771 | 100 mg | $209.00 | 1 | |
Albendazole is an antiparasitic drug that indirectly modulates γ Tubulin by affecting microtubule dynamics. It binds to tubulin, inhibiting microtubule assembly and impacting the microtubule-organizing center where γ Tubulin plays a vital role in microtubule nucleation. | ||||||
Docetaxel | 114977-28-5 | sc-201436 sc-201436A sc-201436B | 5 mg 25 mg 250 mg | $85.00 $325.00 $1072.00 | 16 | |
Docetaxel, a taxane derivative, indirectly influences γ Tubulin by promoting microtubule assembly. By binding to tubulin subunits, docetaxel stabilizes microtubules, affecting the microtubule-organizing center where γ Tubulin is involved in microtubule nucleation. | ||||||
Thiocolchicoside | 602-41-5 | sc-202839 sc-202839A | 1 mg 5 mg | $30.00 $120.00 | ||
Thiocolchicoside is a semi-synthetic derivative of colchicine that indirectly modulates γ Tubulin by affecting microtubule dynamics. It binds to tubulin and interferes with microtubule assembly, impacting the microtubule-organizing center where γ Tubulin plays a key role in microtubule nucleation. | ||||||