Date published: 2026-5-30

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Gγ 7 Inhibitors

Gγ 7 inhibitors belong to a class of chemical compounds designed to selectively target and modulate the activity of the Gγ 7 protein. Gγ 7, also known as Gamma-7 subunit of G proteins, is a subunit of the heterotrimeric G protein complex. This complex is an integral part of cell signaling pathways and plays a vital role in transducing signals from cell surface receptors to intracellular effectors. G proteins consist of three subunits: α, β, and γ. The Gγ subunit, including Gγ 7, is responsible for anchoring the G protein to the cell membrane and facilitating its interaction with various signaling partners. Inhibitors of Gγ 7 are instrumental in molecular and cellular biology research, allowing scientists to investigate the specific functions and regulatory mechanisms associated with this particular subunit within the broader context of G protein signaling.

The development of Gγ 7 inhibitors typically involves a combination of biochemical, biophysical, and structural techniques aimed at identifying or designing molecules that can bind selectively to Gγ 7 and modulate its activity. By targeting Gγ 7, these inhibitors can disrupt the interactions between G proteins and their downstream signaling partners, thus influencing cellular signaling processes. Researchers use Gγ 7 inhibitors to explore the intricate roles played by G proteins and their subunits, including Gγ 7, in various cellular pathways and physiological responses. Furthermore, these inhibitors serve as valuable tools for dissecting the complex network of cellular processes that rely on G protein-mediated signaling, contributing to our understanding of fundamental cell biology mechanisms and providing insights into avenues for further scientific inquiry.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$74.00
$243.00
$731.00
$2572.00
$21848.00
53
(3)

Binds to DNA and inhibits RNA synthesis, which could decrease Gγ7 subunit expression by preventing transcription.

Triptolide

38748-32-2sc-200122
sc-200122A
1 mg
5 mg
$90.00
$204.00
13
(1)

Acts as a transcription inhibitor and could reduce Gγ7 expression by blocking the transcription of its gene.

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

A DNA methyltransferase inhibitor that may cause hypomethylation of the Gγ7 gene, potentially reducing its expression.

5-Aza-2′-Deoxycytidine

2353-33-5sc-202424
sc-202424A
sc-202424B
25 mg
100 mg
250 mg
$218.00
$322.00
$426.00
7
(1)

Similar to 5-Azacytidine, it could inhibit DNA methyltransferase, possibly leading to reduced expression of the Gγ7 gene.

α-Amanitin

23109-05-9sc-202440
sc-202440A
1 mg
5 mg
$269.00
$1050.00
26
(2)

Inhibits RNA polymerase II, potentially decreasing the transcription of mRNA for the Gγ7 subunit.

Rocaglamide

84573-16-0sc-203241
sc-203241A
sc-203241B
sc-203241C
sc-203241D
100 µg
1 mg
5 mg
10 mg
25 mg
$275.00
$474.00
$1639.00
$2497.00
$5344.00
4
(1)

Inhibits protein synthesis and could non-specifically reduce the expression of the Gγ7 subunit.

Cycloheximide

66-81-9sc-3508B
sc-3508
sc-3508A
100 mg
1 g
5 g
$41.00
$84.00
$275.00
127
(6)

Inhibits eukaryotic protein synthesis and could theoretically lead to a decrease in Gγ7 expression by preventing its translation.

DRB

53-85-0sc-200581
sc-200581A
sc-200581B
sc-200581C
10 mg
50 mg
100 mg
250 mg
$43.00
$189.00
$316.00
$663.00
6
(1)

Inhibits RNA polymerase II and could consequently reduce the expression of the Gγ7 subunit.

Harringtonin

26833-85-2sc-204771
sc-204771A
sc-204771B
sc-204771C
sc-204771D
5 mg
10 mg
25 mg
50 mg
100 mg
$250.00
$367.00
$548.00
$730.00
$980.00
30
(1)

Inhibits protein synthesis by preventing the initial elongation step of translation, which could indirectly reduce Gγ7 subunit levels.

Anisomycin

22862-76-6sc-3524
sc-3524A
5 mg
50 mg
$99.00
$259.00
36
(2)

Inhibits peptide bond formation during protein synthesis, possibly leading to a general decrease in protein levels, including Gγ7.