FSTL4 Activators
FSTL4, or Follistatin-like 4, is a protein encoded by the FSTL4 gene in humans. It belongs to the SPARC (secreted protein, acidic, rich in cysteine) family, which is involved in various cellular processes, including cell communication, proliferation, and differentiation. FSTL4 shares structural similarities with other follistatin proteins, particularly in the follistatin-like domain, which is known to bind and neutralize members of the TGF-β superfamily of growth factors.
The biological functions of FSTL4 are not as well characterized as other family members, but it is thought to play a role in modulating extracellular signals and cellular responses to these signals. FSTL4 may act in a regulatory capacity, influencing tissue remodeling, repair, and fibrosis by affecting the activity of growth factors and cytokines within the extracellular matrix.FSTL4 expression has been detected in various tissues, suggesting a widespread role in human physiology. Its expression can be regulated by a range of internal and external factors, including developmental signals, stress responses, and possibly pathological conditions. Given its involvement in modulating growth factor activity, FSTL4 may have implications in wound healing, cardiovascular diseases, and fibrotic disorders.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
May regulate gene expression through retinoic acid receptors, potentially affecting FSTL4. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Elevates cAMP, which may modulate transcription factors and influence FSTL4 expression. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
Glucocorticoids can regulate gene expression, potentially altering FSTL4 levels. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
Activates protein kinase C, which may lead to transcriptional regulation of FSTL4. | ||||||
Sodium Salicylate | 54-21-7 | sc-3520 sc-3520A sc-3520B sc-3520C | 1 g 25 g 500 g 1 kg | $10.00 $25.00 $80.00 $136.00 | 8 | |
Inhibits NF-κB signaling, potentially influencing FSTL4 transcription. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Modulates transcription factors and signaling pathways, which may alter FSTL4 expression. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Influences GSK-3 signaling, potentially affecting FSTL4 expression. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $62.00 $178.00 | 8 | |
Estrogen receptor signaling can impact gene expression, possibly including FSTL4. | ||||||
Rosiglitazone | 122320-73-4 | sc-202795 sc-202795A sc-202795C sc-202795D sc-202795B | 25 mg 100 mg 500 mg 1 g 5 g | $118.00 $320.00 $622.00 $928.00 $1234.00 | 38 | |
PPAR agonists modulate the expression of genes involved in metabolism and inflammation, potentially affecting FSTL4. | ||||||
25-Hydroxycholesterol | 2140-46-7 | sc-214091B sc-214091 sc-214091A sc-214091C | 5 mg 10 mg 25 mg 100 mg | $52.00 $89.00 $166.00 $465.00 | 8 | |
Oxysterols regulate lipid metabolism and may influence genes involved in lipid signaling pathways, including FSTL4. | ||||||