| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $82.00 $216.00 $416.00 | 48 | |
Inhibits the activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7, which are part of the TGF-β superfamily. This leads to decreased SMAD2/3 phosphorylation and subsequently TGF-β signaling inhibition. | ||||||
SB-505124 | 694433-59-5 | sc-362794 sc-362794A | 10 mg 50 mg | $327.00 $1377.00 | 2 | |
A selective inhibitor of ALK4 and ALK5, which are TGF-β type I receptors. Reduces SMAD2/3 activation by TGF-β. | ||||||
4-(6-(4-(Piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline | 1062368-24-4 | sc-476297 | 5 mg | $240.00 | ||
A selective inhibitor of BMP type I receptors ALK2, ALK3, and ALK6, leading to reduced phosphorylation of SMAD1/5/8 and inhibition of the BMP signaling pathway. | ||||||
ALK5 Inhibitor II | 446859-33-2 | sc-221234 sc-221234A sc-221234B sc-221234C sc-221234D sc-221234E sc-221234F | 1 mg 5 mg 10 mg 50 mg 100 mg 500 mg 1 g | $77.00 $153.00 $219.00 $663.00 $1248.00 $4382.00 $7850.00 | 8 | |
Inhibits the TGF-β type I receptor ALK5, leading to reduced SMAD2/3 activation and TGF-β signaling suppression. | ||||||
GW788388 | 452342-67-5 | sc-363544 sc-363544A | 5 mg 25 mg | $95.00 $384.00 | ||
A potent inhibitor of ALK5 and ALK4, leading to suppression of the TGF-β signaling pathway. Reduces SMAD2/3 phosphorylation. | ||||||
DMH-1 | 1206711-16-1 | sc-361171 sc-361171B sc-361171A sc-361171C | 10 mg 25 mg 50 mg 100 mg | $213.00 $318.00 $632.00 $1047.00 | 2 | |
Selective BMP receptor inhibitor, targeting ALK2, ALK3, and ALK6, leading to the suppression of BMP-induced SMAD1/5/8 phosphorylation. | ||||||
A 83-01 | 909910-43-6 | sc-203791 sc-203791A | 10 mg 50 mg | $202.00 $811.00 | 16 | |
Inhibits ALK4, ALK5, and ALK7, leading to suppression of TGF-β/activin/nodal signaling. It prevents the phosphorylation of SMAD2/3. | ||||||