FRMD6 Activators
Items 1 to 10 of 19 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
ROCK inhibitor, affecting the Hippo pathway and FRMD6. | ||||||
Verteporfin | 129497-78-5 | sc-475698 sc-475698A | 10 mg 100 mg | $354.00 $2764.00 | 5 | |
Disrupts YAP-TEAD interaction, affecting FRMD6 activity. | ||||||
GSK 269962 | 850664-21-0 | sc-363279 sc-363279A | 10 mg 50 mg | $300.00 $1000.00 | 1 | |
GSK269962A inhibits FRMD6 through its interaction with the FRMD6 kinase domain, disrupting its binding to substrates and impeding cell migration and invasion. | ||||||
Doxorubicin | 23214-92-8 | sc-280681 sc-280681A | 1 mg 5 mg | $176.00 $426.00 | 43 | |
Affects the Hippo pathway through DNA intercalation. | ||||||
H-1152 dihydrochloride | 451462-58-1 | sc-203592 sc-203592A | 1 mg 5 mg | $104.00 $364.00 | 7 | |
H-1152 is another Rho kinase inhibitor that indirectly affects FRMD6 by modulating the Rho/ROCK pathway, leading to reduced FRMD6-mediated cell adhesion and migration. | ||||||
Lysophosphatidic Acid | 325465-93-8 | sc-201053 sc-201053A | 5 mg 25 mg | $98.00 $341.00 | 50 | |
Modulates Hippo signaling through G-protein-coupled receptor signaling. | ||||||
RKI-1447 | 1342278-01-6 | sc-472590 | 1 mg | $330.00 | ||
RKI-1447 is a potent inhibitor of the PAK4 kinase, which phosphorylates and activates FRMD6. Inhibiting PAK4 reduces FRMD6 activity, impairing cell migration and metastasis. | ||||||
PF-562271 | 717907-75-0 | sc-478488 sc-478488A sc-478488B | 5 mg 10 mg 50 mg | $312.00 $474.00 $1124.00 | 3 | |
PF-562271 targets the FAK kinase, which can interact with FRMD6 in focal adhesions. Inhibiting FAK disrupts FRMD6's role in cell adhesion and migration processes. | ||||||
Lovastatin | 75330-75-5 | sc-200850 sc-200850A sc-200850B | 5 mg 25 mg 100 mg | $29.00 $90.00 $339.00 | 12 | |
Inhibits HMG-CoA reductase, influencing Hippo signaling. | ||||||
CCG-1423 | 285986-88-1 | sc-205241 sc-205241A | 1 mg 5 mg | $30.00 $90.00 | 8 | |
CCG-1423 inhibits the interaction between FRMD6 and its downstream target Cdc42, impairing the formation of actin-based structures crucial for cell migration and invasion. | ||||||