Date published: 2026-4-6

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FRMD6 Activators

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Items 11 to 19 of 19 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Cyclopamine

4449-51-8sc-200929
sc-200929A
1 mg
5 mg
$94.00
$208.00
19
(1)

Inhibits Hedgehog signaling, which affects the Hippo pathway.

Fluorouracil

51-21-8sc-29060
sc-29060A
1 g
5 g
$37.00
$152.00
11
(1)

Pyrimidine analog, could influence the Hippo pathway.

AZD7762

860352-01-8sc-364423
2 mg
$107.00
(1)

AZD7762 is a potent inhibitor of CHK1, which phosphorylates FRMD6 and regulates its activity. Blocking CHK1 reduces FRMD6-mediated cell migration and invasion in cancer cells.

Colchicine

64-86-8sc-203005
sc-203005A
sc-203005B
sc-203005C
sc-203005D
sc-203005E
1 g
5 g
50 g
100 g
500 g
1 kg
$100.00
$321.00
$2289.00
$4484.00
$18207.00
$34749.00
3
(2)

Inhibits microtubule polymerization, impacts Hippo signaling.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

Impacts mTOR signaling, affecting the Hippo pathway and FRMD6.

VX-11e

896720-20-0sc-507301
10 mg
$180.00
(0)

VX-11e targets the Aurora A kinase, which phosphorylates FRMD6 and affects its function in cell division and migration. Inhibition of Aurora A reduces FRMD6 activity.

Nutlin-3

548472-68-0sc-45061
sc-45061A
sc-45061B
1 mg
5 mg
25 mg
$62.00
$225.00
$779.00
24
(1)

Affects the p53 pathway, could modulate Hippo signaling.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

Elevates cAMP levels, impacting Hippo signaling.

IPA 3

42521-82-4sc-204016
sc-204016A
5 mg
50 mg
$94.00
$458.00
6
(1)

IPA-3 is an inhibitor of PAK1, an upstream regulator of FRMD6. By inhibiting PAK1, it disrupts FRMD6 activation and impairs its role in controlling cell adhesion and migration.