GSK 269962 is a potent rho kinase (ROCK) inhibitor (IC50 = 1.6 and 4 nM for ROCK1 and ROCK2, respectively). This compound displays greater than 30-fold selectivity for ROCK against a panel of Ser/Thr kinases. GSK 269962 induces vasodilation in rat aorta (IC50 = 35 nM).
Soluble in DMSO (100 mM), and ethanol with gentle warming (10 mM).
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn