FOXRED1 Activators
FOXRED1 Activators encompass a range of chemical compounds that indirectly promote the functional activity of FOXRED1 through distinct pathways, primarily related to mitochondrial biogenesis and function. Resveratrol and SRT1720, through the activation of sirtuin pathways, enhance the role of FOXRED1 in mitochondrial electron transport chain complex I assembly. Similarly, NAD+ and its precursor NMN elevate cellular NAD+ levels, crucial for energy metabolism, thus indirectly supporting FOXRED1 activity. Sulforaphane and Curcumin engage the NRF2 and AMPK/PGC-1α pathways, respectively, leading to an upswing in mitochondrial function and biogenesis, which in turn, may augment FOXRED1's role in complex I assembly. The antioxidant properties of Alpha-lipoic acid and Quercetin further activate AMPK and SIRT1 pathways, promoting mitochondrial health and potentially enhancing FOXRED1 functionality.
In addition to these, compounds like PQQ and Coenzyme Q10 sustain mitochondrial health by enhancing biogenesis and efficient electron transport, respectively, which indirectly support the activity of FOXRED1. Metformin, by activating AMPK, contributes to mitochondrial biogenesis, a process essential for maintaining complex I, where FOXRED1 plays a pivotal role. Lastly, Methylene blue provides an alternative electron transport route that can ameliorate dysfunctions in complex I, thereby potentially compensating for deficits in FOXRED1 activity and indirectly sustaining its functional role in mitochondria. Collectively, these compounds, by targeting various aspects of mitochondrial health and energy metabolism, contribute to the overall enhancement of FOXRED1's critical function in the mitochondrial electron transport chain.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol, a polyphenol found in red wine, is known to activate sirtuin pathways, which are implicated in the regulation of mitochondrial function. Enhanced sirtuin activity can lead to improved mitochondrial biogenesis and function, thereby indirectly enhancing the activity of FOXRED1, which is involved in mitochondrial electron transport chain complex I assembly. | ||||||
NAD+, Free Acid | 53-84-9 | sc-208084B sc-208084 sc-208084A sc-208084C sc-208084D sc-208084E sc-208084F | 1 g 5 g 10 g 25 g 100 g 1 kg 5 kg | $56.00 $186.00 $296.00 $655.00 $2550.00 $3500.00 $10500.00 | 4 | |
Nicotinamide adenine dinucleotide (NAD+) is a cofactor found in all living cells and is essential for energy metabolism. Supplementation with NAD+ can improve the function of mitochondria, thereby potentially enhancing the activity of FOXRED1 in its role of maintaining complex I. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Sulforaphane, a compound found in cruciferous vegetables, activates the NRF2 pathway, which regulates the expression of antioxidant proteins that protect against oxidative damage. NRF2 activation can improve mitochondrial function and integrity, indirectly supporting FOXRED1 activity. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin, the active component of turmeric, influences mitochondrial biogenesis through the activation of AMPK and PGC-1α pathways. Improved mitochondrial biogenesis can augment the role of FOXRED1 in complex I assembly. | ||||||
SRT1720 | 1001645-58-4 | sc-364624 sc-364624A | 5 mg 10 mg | $193.00 $357.00 | 13 | |
SRT1720 is a sirtuin-activating compound that targets SIRT1, promoting mitochondrial function and biogenesis. By enhancing mitochondrial function, SRT1720 may indirectly increase the activity of FOXRED1. | ||||||
α-Lipoic Acid | 1077-28-7 | sc-202032 sc-202032A sc-202032B sc-202032C sc-202032D | 5 g 10 g 250 g 500 g 1 kg | $68.00 $120.00 $208.00 $373.00 $702.00 | 3 | |
Alpha-lipoic acid is an antioxidant that improves mitochondrial function and has been shown to activate AMPK. Activation of AMPK can lead to enhanced mitochondrial biogenesis, supporting the role of FOXRED1 in complex I assembly. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin is a flavonoid with antioxidant properties that can stimulate mitochondrial biogenesis through the activation of SIRT1 and PGC-1α. This may lead to an indirect enhancement of FOXRED1 activity. | ||||||
Pyrroloquinoline quinone | 72909-34-3 | sc-210178 | 1 mg | $238.00 | ||
PQQ is a redox cofactor that has been shown to enhance mitochondrial biogenesis and function. Enhanced mitochondrial function can support the activity of FOXRED1 in electron transport chain maintenance. | ||||||
Coenzyme Q10 | 303-98-0 | sc-205262 sc-205262A | 1 g 5 g | $70.00 $180.00 | 1 | |
Coenzyme Q10 is an essential cofactor for electron transport in mitochondria and is known to support mitochondrial health. By maintaining electron transport chain function, Coenzyme Q10 can indirectly support FOXRED1 activity. | ||||||
Metformin | 657-24-9 | sc-507370 | 10 mg | $77.00 | 2 | |
Metformin is a drug that activates AMPK, a nutrient and energy sensor that stimulates mitochondrial biogenesis. This activation can support FOXRED1 function in maintaining mitochondrial complex I. | ||||||