FOXJ3 Activators
FOXJ3 activators are compounds that can induce the expression or functional activity of FOXJ3 through indirect interactions with cellular signaling pathways. These activators work by modulating the intracellular environment or by influencing the signal transduction processes that govern the activity of various transcription factors, including FOXJ3.
Chemicals like retinoic acid and sulforaphane can exert their influence on FOXJ3 by altering the transcriptional landscape, which includes genes that FOXJ3 may regulate. These compounds may modify the expression levels of FOXJ3 itself or affect its post-translational modifications, thereby impacting its activity as a transcription factor. Other compounds, such as the inhibitors PD98059 and LY294002, can modify kinase activity within cells, leading to altered phosphorylation states of proteins that interface with FOXJ3, either enhancing its stability, facilitating its localization to the nucleus, or increasing its binding to DNA. The use of histone deacetylase inhibitors like trichostatin A and sodium butyrate suggests a role for chromatin remodeling in modulating FOXJ3 activity, thereby promoting the transcription of genes under its control.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
A derivative of vitamin A that can influence gene expression and modulate differentiation pathways that may upregulate FOXJ3. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
A polyphenol from green tea that can alter antioxidant response elements and could influence FOXJ3 activity. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
A bioactive compound from turmeric that modulates various transcription factors and signaling pathways, possibly affecting FOXJ3. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
A stilbenoid that activates sirtuins and could impact signaling pathways involving FOXJ3. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
A compound in cruciferous vegetables that may activate Nrf2 signaling, potentially influencing FOXJ3 expression. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
A DNA methyltransferase inhibitor that can alter gene expression patterns, potentially leading to FOXJ3 activation. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Histone deacetylase inhibitor that changes chromatin structure, potentially enhancing FOXJ3 expression. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
Histone deacetylase inhibitor that could increase transcription of genes including those regulated by FOXJ3. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
A chemical that can activate Wnt signaling pathway, which in turn may indirectly upregulate FOXJ3. | ||||||