Date published: 2025-12-24

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FOXD4L3 Inhibitors

FOXD4L3 inhibitors belong to a specialized class of chemical compounds designed to selectively modulate the activity of the Forkhead Box D4-like 3 (FOXD4L3) protein. This protein is a member of the FOX (Forkhead box) family of transcription factors, known for their roles in regulating gene expression and cellular processes. Despite the presence of conserved DNA-binding domains within the FOXD4L3 protein, its specific functions and molecular targets remain relatively understudied. The inhibitors developed for FOXD4L3 exhibit a distinct chemical structure enabling them to interact selectively with defined binding sites on the FOXD4L3 protein, thereby influencing its molecular activities within the cellular context. The careful design of these inhibitors is crucial for ensuring a high degree of specificity, minimizing unintended effects on other cellular components or transcription factors within the broader FOX family.

The mechanism of action of FOXD4L3 inhibitors involves disrupting the normal functioning of the FOXD4L3 protein, potentially impacting gene regulatory pathways and cellular processes governed by this transcription factor. As researchers explore the complexities of transcriptional regulation and the diverse roles played by FOX family members, FOXD4L3 inhibitors serve as valuable tools, allowing for the investigation of the precise molecular mechanisms controlled by FOXD4L3. The study of this chemical class contributes to a deeper understanding of the role played by FOXD4L3 in cellular physiology, offering insights into its potential functions within the intricate networks that regulate gene expression and cellular responses. Overall, the exploration of FOXD4L3 inhibitors provides a platform for advancing our understanding of the molecular landscape surrounding FOX transcription factors and their nuanced roles in cellular processes.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Triptolide

38748-32-2sc-200122
sc-200122A
1 mg
5 mg
$88.00
$200.00
13
(1)

A diterpene triepoxide that inhibits RNA polymerase II, potentially reducing transcription of many genes, including FOXD4L3.

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$73.00
$238.00
$717.00
$2522.00
$21420.00
53
(3)

An antibiotic that intercalates into DNA and prevents RNA synthesis, which could decrease FOXD4L3 expression.

α-Amanitin

23109-05-9sc-202440
sc-202440A
1 mg
5 mg
$260.00
$1029.00
26
(2)

A toxin from the Amanita mushroom that can inhibit RNA polymerase II, which may reduce the expression of FOXD4L3.

Siomycin A

12656-09-6sc-202339
sc-202339-CW
sc-202339A
sc-202339B
500 µg
500 µg
2.5 mg
25 mg
$439.00
$449.00
$1326.00
$10200.00
4
(1)

A thiazole antibiotic that can inhibit FOXM1, a member of the FOX family, thus may also affect FOXD4L3 expression.

Flavopiridol

146426-40-6sc-202157
sc-202157A
5 mg
25 mg
$78.00
$254.00
41
(3)

A cyclin-dependent kinase inhibitor that can inhibit transcription and potentially reduce FOXD4L3 expression.

Rocaglamide

84573-16-0sc-203241
sc-203241A
sc-203241B
sc-203241C
sc-203241D
100 µg
1 mg
5 mg
10 mg
25 mg
$270.00
$465.00
$1607.00
$2448.00
$5239.00
4
(1)

A natural product that inhibits translation and could also decrease the expression of various proteins, including FOXD4L3.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$42.00
$72.00
$124.00
$238.00
$520.00
$1234.00
11
(1)

A polyphenol found in green tea that has been shown to modulate gene expression and might influence FOXD4L3 expression.

C646

328968-36-1sc-364452
sc-364452A
10 mg
50 mg
$260.00
$925.00
5
(1)

A competitive inhibitor of p300/CBP histone acetyltransferase, which might alter gene expression including that of FOXD4L3.

MS-275

209783-80-2sc-279455
sc-279455A
sc-279455B
1 mg
5 mg
25 mg
$24.00
$88.00
$208.00
24
(2)

A benzamide histone deacetylase inhibitor that can change gene expression profiles, possibly affecting FOXD4L3.

Anacardic Acid

16611-84-0sc-202463
sc-202463A
5 mg
25 mg
$100.00
$200.00
13
(1)

A natural compound that inhibits histone acetyltransferase and may change expression patterns of various genes.