FLJ45513 Inhibitors
FLJ45513 inhibitors like Staurosporine are well-known kinase inhibitor that can alter the phosphorylation state of proteins, a modification that is critical for protein function. Similarly, U0126 and SB431542 can inhibit MEK1/2 and TGF-β signaling, respectively, pathways that are intimately connected with the control of gene expression and protein activity. Compounds like SP600125 and LY333531 target the JNK pathway and protein kinase C β, respectively, both of which are involved in regulating transcription factors and other proteins. PP2, by inhibiting Src family kinases, and PD173074, by targeting FGFR, can affect multiple downstream proteins through complex signaling networks.
Furthermore, Y-27632 and ZM447439 can influence the cytoskeleton and cell cycle progression, respectively, thereby potentially altering the function and localization of proteins. Dorsomorphin and XAV939, as well as IWP-2, target BMP and Wnt/β-catenin signaling pathways, which are crucial for cell differentiation, growth, and development. These pathways are connected to the regulation of numerous proteins, and their inhibition can have widespread effects on protein function.
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
A potent kinase inhibitor that can disrupt various signaling pathways influencing protein activity. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $82.00 $216.00 $416.00 | 48 | |
Inhibits the TGF-β signaling pathway, which can affect cellular processes and protein interactions. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
Inhibits JNK, potentially affecting AP-1 transcription factor activity and protein expression. | ||||||
LY-333,531 Hydrochloride | 169939-93-9 | sc-364215 sc-364215A | 1 mg 5 mg | $94.00 $287.00 | 6 | |
A selective inhibitor of protein kinase C β, which can alter signaling pathways controlling protein function. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $94.00 $227.00 | 30 | |
Inhibits Src family kinases, potentially affecting multiple signaling pathways and protein activity. | ||||||
PD173074 | 219580-11-7 | sc-202610 sc-202610A sc-202610B | 1 mg 5 mg 50 mg | $47.00 $143.00 $680.00 | 16 | |
FGFR inhibitor that can disrupt growth factor signaling, potentially influencing protein interactions. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
Inhibits ROCK, which can affect cytoskeleton dynamics and thus protein localization and function. | ||||||
ZM-447439 | 331771-20-1 | sc-200696 sc-200696A | 1 mg 10 mg | $153.00 $356.00 | 15 | |
Inhibits Aurora kinases, potentially affecting cell cycle progression and protein phosphorylation. | ||||||
BML-275 | 866405-64-3 | sc-200689 sc-200689A | 5 mg 25 mg | $96.00 $355.00 | 69 | |
Inhibits BMP signaling, which can affect gene expression and protein function. | ||||||
XAV939 | 284028-89-3 | sc-296704 sc-296704A sc-296704B | 1 mg 5 mg 50 mg | $36.00 $117.00 $525.00 | 26 | |
Inhibits Wnt/β-catenin signaling, potentially affecting protein levels and interactions. | ||||||