Ficolin B activators are a diverse set of chemical compounds that enhance the functional activity of ficolin B through various biochemical mechanisms. Curcumin, known for its immunomodulatory effects, can increase the opsonization capability of ficolin B, a critical step in the lectin pathway of complement activation. This enhancement facilitates the immune system's ability to mark pathogens for destruction. Similarly, Vitamin D3's modulation of immune responses includes augmenting the expression of proteins in the complement system, which could potentiate the role of ficolin B. Eicosapentaenoic acid, by influencing the formation of resolvins, may enhance ficolin B function indirectly by modulating the complement system. Glucosamine, involved in the biosynthesis of glycosaminoglycans, could bind to ficolin B, thus improving its pathogen recognition and binding efficiency. The role of zinc in stabilizing complement proteins suggests that adequate levels of zinc could improve ficolin B's structural integrity and function within the lectin pathway.
Additionally, Glycyrrhizin's enhancement of phagocytosis could indirectly increase the activity of ficolin B by promoting the clearance of pathogens opsonized by ficolin B. The micronutrient selenium is vital for maintaining the immune function and may enhance ficolin B activity by ensuring the stability of complement proteins. Resveratrol and luteolin, both with anti-inflammatory properties, could support the complement system and ficolin B activity by modulating inflammatory responses. N-Acetylcysteine, by influencing the redox state, may preserve ficolin B functionality, while alpha-lipoic acid supports the complement system's overall antioxidant capacity. Lastly, quercetin could stabilize ficolin B and other proteins involved in the lectin pathway, ensuring efficient complement activation.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin, a bioactive compound found in turmeric, has been shown to activate the lectin pathway of complement, in which ficolin B participates. Curcumin binds to pattern recognition molecules and can enhance the opsonization of pathogens, thereby indirectly increasing the functional activity of ficolin B. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $70.00 $160.00 $290.00 | 2 | |
Vitamin D3 modulates the immune system and has been reported to enhance the expression of complement proteins. It influences the alternative complement pathway, which has a synergistic relationship with the lectin pathway where ficolin B is active, thus potentially enhancing ficolin B activity. | ||||||
Eicosa-5Z,8Z,11Z,14Z,17Z-pentaenoic Acid (20:5, n-3) | 10417-94-4 | sc-200766 sc-200766A | 100 mg 1 g | $102.00 $423.00 | ||
EPA, an omega-3 fatty acid, has anti-inflammatory properties and is involved in the formation of resolvins which modulate the complement system. EPA may influence the lectin pathway by altering the lipid environment of pattern recognition molecules, including ficolin B. | ||||||
D-Glucosamine | 3416-24-8 | sc-278917A sc-278917 | 1 g 10 g | $197.00 $764.00 | ||
Glucosamine is involved in the biosynthesis of glycosaminoglycans, which can bind to ficolin B and modulate its function. This interaction may enhance the ability of ficolin B to bind to pathogens and activate the lectin pathway. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Zinc is essential for the proper function of the immune system and is known to play a role in the stabilization of complement proteins. Zinc supplementation could enhance the structural integrity of ficolin B, leading to better functionality in the lectin pathway. | ||||||
Glycyrrhizic acid | 1405-86-3 | sc-279186 sc-279186A | 1 g 25 g | $56.00 $326.00 | 7 | |
Glycyrrhizin, found in licorice root, has immunomodulatory effects, including the enhancement of phagocytosis. It may indirectly increase ficolin B activity by promoting the clearance of pathogens that ficolin B has opsonized. | ||||||
Selenium | 7782-49-2 | sc-250973 | 50 g | $61.00 | 1 | |
Selenium is a micronutrient that is crucial for immune function. It has been shown to enhance the activity of complement proteins, potentially including ficolin B, by maintaining their redox state and stability. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol is a polyphenolic compound with significant anti-inflammatory properties. It may enhance the activity of ficolin B by modulating signaling pathways that influence the synthesis and function of complement proteins. | ||||||
Luteolin | 491-70-3 | sc-203119 sc-203119A sc-203119B sc-203119C sc-203119D | 5 mg 50 mg 500 mg 5 g 500 g | $26.00 $50.00 $99.00 $150.00 $1887.00 | 40 | |
Luteolin is a flavonoid with anti-inflammatory and antioxidant properties. It may enhance the functionality of ficolin B by modulating inflammatory responses and maintaining the stability of complement proteins. | ||||||
N-Acetyl-L-cysteine | 616-91-1 | sc-202232 sc-202232A sc-202232C sc-202232B | 5 g 25 g 1 kg 100 g | $33.00 $73.00 $265.00 $112.00 | 34 | |
NAC has antioxidant properties and is known to influence the redox state of cells. By maintaining the reducing environment, it may preserve the functionality of complement proteins, including ficolin B. | ||||||