Date published: 2026-5-30

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FEM1A Inhibitors

FEM1A inhibitors encompass a variety of chemicals that are not directly targeted against FEM1A but exert their influence by modulating associated signaling pathways or cellular processes. Staurosporine, a potent kinase inhibitor, stands out in this category, known for its broad-spectrum induction of apoptosis in diverse cells. Its function indirectly reduces FEM1A activity by steering cells towards death. Similarly, the JNK inhibitor, SP600125, can reshape the apoptotic landscape within the cell and indirectly modulate FEM1A, considering the connection between JNK and apoptosis. Furthermore, the intricate web of apoptotic signaling has been targeted by several other compounds. LY294002, a PI3K inhibitor, and PD98059, an ERK pathway inhibitor, both have the potential to modulate FEM1A activity indirectly due to their roles in apoptotic pathways. Meanwhile, the influence of BAY 11-7082 on the NF-κB pathway and SB203580 on p38 MAPK offers alternative routes to indirectly affect FEM1A. These compounds underscore the complexity and interconnectedness of cellular signaling.

Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Staurosporine

62996-74-1sc-3510
sc-3510A
sc-3510B
100 µg
1 mg
5 mg
$82.00
$153.00
$396.00
113
(4)

Kinase inhibitor that induces apoptosis in various cells. By promoting cell death, it can indirectly reduce FEM1A activity.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

JNK inhibitor. Given the role of JNK in apoptosis, inhibiting JNK can indirectly modulate FEM1A-associated apoptosis.

Z-VAD-FMK

187389-52-2sc-3067
500 µg
$75.00
256
(6)

Pan-caspase inhibitor. By inhibiting caspase activation, it can modulate the apoptotic processes linked to FEM1A.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

PI3K inhibitor. FEM1A might be indirectly modulated when key apoptotic pathways influenced by PI3K are inhibited.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$40.00
$92.00
212
(2)

ERK pathway inhibitor. Since ERK is implicated in apoptosis, its inhibition can indirectly influence FEM1A activity.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$90.00
$349.00
284
(5)

p38 MAPK inhibitor. Inhibition of p38 might impact FEM1A's role in apoptosis indirectly.

BAY 11-7082

19542-67-7sc-200615B
sc-200615
sc-200615A
5 mg
10 mg
50 mg
$62.00
$85.00
$356.00
155
(1)

NF-κB pathway inhibitor. Affecting this pathway might indirectly influence apoptotic processes associated with FEM1A.

MG-132 [Z-Leu- Leu-Leu-CHO]

133407-82-6sc-201270
sc-201270A
sc-201270B
5 mg
25 mg
100 mg
$60.00
$265.00
$1000.00
163
(3)

Proteasome inhibitor. By inhibiting proteasomal degradation, it can potentially modulate proteins like FEM1A.

Cycloheximide

66-81-9sc-3508B
sc-3508
sc-3508A
100 mg
1 g
5 g
$41.00
$84.00
$275.00
127
(6)

Protein synthesis inhibitor. Indirectly affects FEM1A levels by halting its production.

Thapsigargin

67526-95-8sc-24017
sc-24017A
1 mg
5 mg
$136.00
$446.00
114
(2)

ER calcium ATPase inhibitor. Impacts calcium-dependent apoptotic processes, possibly influencing FEM1A activity.