Fatty Acid Synthase Inhibitors
Items 1 to 10 of 14 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
BML-275 | 866405-64-3 | sc-200689 sc-200689A | 5 mg 25 mg | $94.00 $348.00 | 69 | |
BML-275 is a selective inhibitor of fatty acid synthase, exhibiting unique binding interactions that disrupt the enzyme's catalytic activity. Its structure allows for specific interactions with the active site, altering the enzyme's conformation and inhibiting substrate access. The compound's kinetic profile reveals a competitive inhibition mechanism, impacting lipid biosynthesis pathways. Additionally, BML-275's hydrophobic characteristics enhance its affinity for lipid membranes, influencing cellular uptake and distribution. | ||||||
Cerulenin (synthetic) | 17397-89-6 | sc-200827 sc-200827A sc-200827B | 5 mg 10 mg 50 mg | $158.00 $306.00 $1186.00 | 9 | |
A natural product that specifically inhibits FASN activity, leading to reduced fatty acid synthesis. | ||||||
Kaempferol | 520-18-3 | sc-202679 sc-202679A sc-202679B | 25 mg 100 mg 1 g | $97.00 $212.00 $500.00 | 11 | |
Kaempferol acts as a modulator of fatty acid synthase, engaging in unique non-covalent interactions that stabilize the enzyme's structure. Its presence can alter the enzyme's allosteric sites, leading to changes in reaction kinetics and substrate affinity. This flavonoid influences lipid metabolism by affecting the enzyme's regulatory pathways, potentially shifting the balance of fatty acid production. Its hydrophilic and lipophilic properties facilitate diverse interactions within cellular environments. | ||||||
C75 (racemic) | 191282-48-1 | sc-202511 sc-202511A sc-202511B | 1 mg 5 mg 10 mg | $71.00 $202.00 $284.00 | 9 | |
A synthetic compound that inhibits FASN and induces apoptosis in cancer cells. | ||||||
Quercetin Dihydrate | 6151-25-3 | sc-203225 sc-203225A | 5 g 25 g | $35.00 $60.00 | 1 | |
Quercetin Dihydrate functions as a modulator of fatty acid synthase, exhibiting distinct binding affinities that influence enzyme conformation. It interacts with specific amino acid residues, enhancing or inhibiting catalytic activity through allosteric modulation. This flavonoid can impact lipid biosynthesis by altering metabolic flux, while its dual solubility characteristics enable it to navigate complex cellular environments, facilitating diverse biochemical interactions. | ||||||
Luteolin | 491-70-3 | sc-203119 sc-203119A sc-203119B sc-203119C sc-203119D | 5 mg 50 mg 500 mg 5 g 500 g | $26.00 $50.00 $99.00 $150.00 $1887.00 | 40 | |
A flavonoid that can suppress FASN expression and influence lipid metabolism. | ||||||
Lipase Inhibitor, THL | 96829-58-2 | sc-203108 | 50 mg | $51.00 | 7 | |
Lipase Inhibitor, THL inhibits FASN, impacting lipid metabolism. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
Epigallocatechin gallate, a green tea polyphenol, has been shown to inhibit FASN expression. | ||||||
Pyrazinamide | 98-96-4 | sc-205824 sc-205824A sc-205824B sc-205824C sc-205824D sc-205824E | 10 g 25 g 100 g 250 g 1 kg 5 kg | $48.00 $66.00 $87.00 $148.00 $474.00 $2231.00 | ||
Pyrazinamide acts as a unique inhibitor of fatty acid synthase, engaging in specific interactions with the enzyme's active site. Its structural features allow it to disrupt the enzyme's catalytic cycle, leading to altered reaction kinetics. By stabilizing certain conformations, it can modulate the accessibility of substrates, thereby influencing lipid metabolism pathways. Additionally, its hydrophilic nature aids in solubility, promoting effective distribution within cellular compartments. | ||||||
Triclosan | 3380-34-5 | sc-220326 sc-220326A | 10 g 100 g | $138.00 $400.00 | ||
An antibacterial agent, triclosan also inhibits FASN. | ||||||