FARP2 Inhibitors
FARP2 inhibitors target and inhibit the function of FERM, RhoGEF, and pleckstrin domain protein 2 (FARP2). FARP2 is a multifunctional enzyme that plays a crucial role in intracellular signaling pathways, particularly those involving cytoskeletal dynamics and cell morphology. It acts as a guanine nucleotide exchange factor (GEF) for certain members of the Rho family of GTPases, which are key regulators of the actin cytoskeleton. The inhibition of FARP2 by these compounds is significant as it can influence the enzyme's role in actin cytoskeleton reorganization and various cellular processes. The molecular structure of FARP2 inhibitors is characterized by specific features that allow for effective and selective interaction with the enzyme. These inhibitors typically contain functional groups that can bind to the GEF domain of FARP2, thereby inhibiting its catalytic activity.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Mycophenolic acid | 24280-93-1 | sc-200110 sc-200110A | 100 mg 500 mg | $68.00 $261.00 | 8 | |
An inhibitor of inosine monophosphate dehydrogenase, potentially affecting RNA synthesis and thereby FARP2 expression. | ||||||
Flavopiridol | 146426-40-6 | sc-202157 sc-202157A | 5 mg 25 mg | $78.00 $254.00 | 41 | |
A cyclin-dependent kinase inhibitor that can arrest cell cycle progression and potentially downregulate FARP2 expression. | ||||||
Mitomycin C | 50-07-7 | sc-3514A sc-3514 sc-3514B | 2 mg 5 mg 10 mg | $65.00 $99.00 $140.00 | 85 | |
Forms crosslinks in DNA, possibly disrupting transcription and affecting FARP2 expression. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
May modulate transcription factor activity and chromatin structure, potentially influencing FARP2 expression. | ||||||
Sulfasalazine | 599-79-1 | sc-204312 sc-204312A sc-204312B sc-204312C | 1 g 2.5 g 5 g 10 g | $60.00 $75.00 $125.00 $205.00 | 8 | |
Has been shown to inhibit NF-κB, a transcription factor that could be involved in FARP2 expression regulation. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $97.00 $254.00 | 36 | |
Inhibits protein synthesis at the level of peptide chain elongation, which could indirectly decrease FARP2 expression. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $68.00 | 2 | |
Affects DNA and RNA synthesis by intercalation, which could alter transcription and reduce FARP2 expression. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $54.00 | 6 | |
Binds to DNA and inhibits RNA synthesis, potentially leading to decreased expression of FARP2. | ||||||
Oligomycin A | 579-13-5 | sc-201551 sc-201551A sc-201551B sc-201551C sc-201551D | 5 mg 25 mg 100 mg 500 mg 1 g | $175.00 $600.00 $1179.00 $5100.00 $9180.00 | 26 | |
Inhibits ATP synthase, decreasing cellular ATP levels and potentially affecting transcription and FARP2 expression. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $260.00 $1029.00 | 26 | |
A potent inhibitor of RNA polymerase II, which could result in decreased transcription of FARP2 mRNA. | ||||||