Date published: 2025-10-15

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FAM90A Inhibitors

FAM90A inhibitors encompass a range of chemical entities that impede the functional activity of the protein through various biochemical mechanisms. These inhibitors target key signaling pathways and kinases, which are instrumental in regulating the functional state of FAM90A. Some inhibitors act by obstructing kinase activity, which is essential for the phosphorylation events that activate FAM90A, leading to a reduction in the protein's activity. Others specifically target the mTOR pathway, a signaling cascade integral to cell growth and survival. By doing so, they indirectly influence the activity of FAM90A, which may be regulated by components of this pathway. Additionally, the inhibition of the PI3K/AKT pathway, a critical axis in cell signaling, results in the diminishment of downstream effects, potentially affecting the functional state of FAM90A. Further, compounds that impede the MAPK/ERK and stress-activated MAPK pathways have been identified, which could diminish the activity of FAM90A if it is modulated by these signaling routes. Inhibition of JNK and p38 MAPK also contribute to the dampening of FAM90A activity by affecting stress and inflammation-related pathways that may intersect with FAM90A's regulatory roles. This indicates that FAM90A's activity could be linked with cellular responses to environmental stimuli, and modulating these pathways can indirectly suppress its function. Moreover, by targeting these kinases and signaling cascades, these inhibitors may alter the phosphorylation pattern of FAM90A, affecting its stability, localization, or interaction with other proteins, thus further influencing its role in cellular processes.

Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Staurosporine

62996-74-1sc-3510
sc-3510A
sc-3510B
100 µg
1 mg
5 mg
$82.00
$150.00
$388.00
113
(4)

Staurosporine is a potent inhibitor of protein kinases. Its inhibition of kinase activity can reduce the phosphorylation of FAM90A, thereby decreasing its functional activity.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$62.00
$155.00
$320.00
233
(4)

Rapamycin selectively inhibits mTOR, a kinase that is part of a critical cell growth and survival pathway. By inhibiting this pathway, the activity of downstream proteins like FAM90A that may be regulated by mTOR activity can be indirectly reduced.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$121.00
$392.00
148
(1)

LY 294002 is a PI3K inhibitor, and by inhibiting PI3K, it impairs the downstream AKT signaling pathway. This can lead to reduced phosphorylation and activation of proteins that are regulated by AKT, potentially including FAM90A.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$39.00
$90.00
212
(2)

PD 98059 is an MEK inhibitor that disrupts the MAPK/ERK pathway. By inhibiting this pathway, it could indirectly inhibit the activity of FAM90A if it is downstream of ERK signaling.

U-0126

109511-58-2sc-222395
sc-222395A
1 mg
5 mg
$63.00
$241.00
136
(2)

U0126 is an MEK inhibitor that works by inhibiting the MAPK/ERK pathway. This inhibition can decrease the activity of proteins like FAM90A if they are involved in or regulated by this pathway.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

SP600125 is an inhibitor of JNK, a kinase involved in the stress-activated MAPK pathway. Inhibition of JNK could lead to decreased functional activity of FAM90A if it is a downstream target of JNK signaling.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$88.00
$342.00
284
(5)

SB 203580 is a p38 MAPK inhibitor which, by inhibiting p38 MAPK signaling, could lead to reduced activity of proteins like FAM90A that may be modulated by this pathway.

Wortmannin

19545-26-7sc-3505
sc-3505A
sc-3505B
1 mg
5 mg
20 mg
$66.00
$219.00
$417.00
97
(3)

Wortmannin is a potent inhibitor of PI3K. By inhibiting PI3K, it impairs the PI3K/AKT pathway and can lead to reduced activity of downstream proteins potentially regulated by this pathway, such as FAM90A.

Triciribine

35943-35-2sc-200661
sc-200661A
1 mg
5 mg
$102.00
$138.00
14
(1)

Triciribine specifically inhibits AKT activation. By doing so, it can affect downstream signaling pathways and proteins that are regulated by AKT, potentially including FAM90A.

Bisindolylmaleimide I (GF 109203X)

133052-90-1sc-24003A
sc-24003
1 mg
5 mg
$103.00
$237.00
36
(1)

Bisindolylmaleimide I is a specific inhibitor of PKC, which is involved in various signaling pathways. Inhibition of PKC could lead to decreased phosphorylation and activity of proteins like FAM90A if they are downstream of PKC signaling.