FAM75D3 Activators
FAM75D3 Activators encompass a diverse array of chemical compounds that can indirectly stimulate the functional activity of FAM75D3 through their respective signaling pathways. Forskolin, by raising intracellular cAMP levels, may enhance FAM75D3's activity through PKA-dependent phosphorylation events. Genistein, as a tyrosine kinase inhibitor, indirectly amplifies FAM75D3's activity within its specific pathways by reducing competitive tyrosine kinase signaling. The lipid signaling mediator Sphingosine-1-phosphate and the SERCA pump inhibitor Thapsigargin both utilize lipid and calcium signaling, respectively, to potentially bolster the processes involving FAM75D3. FAM75D3 Activators are a diverse range of chemical compounds that indirectly enhance the functional activity of FAM75D3 through a variety of signaling pathways.
Forskolin, by elevating intracellular cAMP levels, can indirectly upregulate FAM75D3's activity through PKA-mediated phosphorylation, while Genistein, acting as a tyrosine kinase inhibitor, diminishes competitive signaling pathways, which may result in the preferential activation of pathways involving FAM75D3. The lipid signaling molecule Sphingosine-1-phosphate, through its receptor-mediated pathway activation, can potentiate cellular processes that FAM75D3 is part of, potentially leading to increased activity of FAM75D3. Thapsigargin and A23187 both increase intracellular calcium levels, which could enhance FAM75D3's function if it is involved in calcium-dependent signaling pathways. Similarly, PMA, which activates PKC, and Epigallocatechin gallate (EGCG), a kinase inhibitor, could facilitate the phosphorylation of substrates in pathways where FAM75D3 is active, thereby amplifying its functional role.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein is a tyrosine kinase inhibitor that can reduce competitive signaling pathways by inhibiting tyrosine kinases. This may result in an indirect enhancement of FAM75D3's activity by allowing more resources or signaling capacity to be directed toward pathways where FAM75D3 is active. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $162.00 $316.00 $559.00 $889.00 $1693.00 | 7 | |
Sphingosine-1-phosphate (S1P) engages S1P receptors leading to downstream signaling cascades that can include PLC activation and calcium release. This signaling can potentiate cellular processes where FAM75D3 is involved, potentially enhancing its activity. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
Thapsigargin, a SERCA inhibitor, leads to an increase in cytosolic calcium levels, activating calcium-dependent proteins and signaling pathways. This increase in calcium signaling might indirectly enhance the functional activity of FAM75D3 if it is involved in calcium-dependent processes. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA is a potent activator of protein kinase C (PKC), which phosphorylates various substrates. PKC-mediated phosphorylation could enhance the activity of FAM75D3 if it is involved in PKC-regulated pathways or processes. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a PI3K inhibitor, which can lead to reduced Akt signaling. This alteration in signaling dynamics may indirectly increase the functional activity of FAM75D3 through a compensatory mechanism within the pathways that FAM75D3 participates. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin is another PI3K inhibitor, similar in function to LY294002, and it can also modulate downstream signaling in a way that could potentially enhance the activity of FAM75D3. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 is a p38 MAPK inhibitor and can shift the signaling equilibrium in the cell. By inhibiting p38 MAPK, it could enhance signaling pathways where FAM75D3 is active, if FAM75D3 operates in a pathway that is negatively regulated by p38 MAPK. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
U0126 is an inhibitor of MEK1/2, which are upstream of ERK in the MAPK pathway. Inhibition of MEK can lead to changes in signaling that might enhance the activity of FAM75D3 if it is involved in ERK-regulated processes. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $54.00 $128.00 $199.00 $311.00 | 23 | |
A23187 is an ionophore that selectively increases intracellular calcium levels. This elevation in calcium could activate pathways or proteins that are involved in the same processes as FAM75D3, thereby enhancing its functional activity. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG is a kinase inhibitor that can modulate various signaling pathways. By inhibiting competitive kinases, EGCG could lead to an enhancement of FAM75D3's activity if FAM75D3 operates within the affected pathways or processes. | ||||||