Date published: 2025-10-10

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FAM65A Inhibitors

FAM65A inhibitors are a class of chemical compounds that specifically target and inhibit the activity of the FAM65A protein, a member of the FAM65 family, which is involved in the regulation of various cellular processes, particularly those associated with cell motility, cytoskeletal dynamics, and signal transduction. FAM65A is known to interact with key components of the cytoskeleton and other regulatory proteins, playing a critical role in maintaining cell shape, facilitating cell movement, and possibly influencing the organization of cellular structures. This protein is also implicated in the regulation of signaling pathways that control cell behavior, including processes such as polarization, migration, and the response to external stimuli. The inhibition of FAM65A can therefore have significant effects on cellular architecture and function. The mechanism by which FAM65A inhibitors exert their effects typically involves binding to specific regions of the FAM65A protein, such as domains that are crucial for its interaction with other proteins or its role in cytoskeletal organization. By inhibiting FAM65A, these compounds can disrupt the normal functioning of the cytoskeleton, leading to changes in cell morphology, impaired cellular motility, and potential disruptions in signal transduction pathways. This inhibition can also affect the cell's ability to maintain its structural integrity and respond to environmental cues, which can have wide-ranging implications for cellular processes like division, migration, and tissue organization. Studying the effects of FAM65A inhibition provides valuable insights into the specific roles of this protein in cellular physiology, helping to elucidate the complex interactions that govern cytoskeletal dynamics and the overall behavior of cells within their environments. Understanding these mechanisms is crucial for advancing our knowledge of how cells regulate their shape, movement, and internal organization in response to various physiological demands.

Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Wortmannin

19545-26-7sc-3505
sc-3505A
sc-3505B
1 mg
5 mg
20 mg
$66.00
$219.00
$417.00
97
(3)

A phosphoinositide 3-kinase (PI3K) inhibitor that can disrupt signaling pathways, possibly affecting FAM65A-involved pathways.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$121.00
$392.00
148
(1)

Another PI3K inhibitor that can block PI3K-dependent signaling, potentially altering FAM65A-related activity.

Taxol

33069-62-4sc-201439D
sc-201439
sc-201439A
sc-201439E
sc-201439B
sc-201439C
1 mg
5 mg
25 mg
100 mg
250 mg
1 g
$40.00
$73.00
$217.00
$242.00
$724.00
$1196.00
39
(2)

Stabilizes microtubules and can disrupt cytoskeletal dynamics, potentially influencing FAM65A if it interacts with the cytoskeleton.

Nocodazole

31430-18-9sc-3518B
sc-3518
sc-3518C
sc-3518A
5 mg
10 mg
25 mg
50 mg
$58.00
$83.00
$140.00
$242.00
38
(2)

A microtubule-depolymerizing agent that can alter cytoskeletal organization, possibly affecting FAM65A's role in cellular structure.

1-β-D-Arabinofuranosylcytosine

147-94-4sc-201628
sc-201628A
sc-201628B
sc-201628C
sc-201628D
1 g
5 g
25 g
100 g
250 g
$147.00
$258.00
$508.00
$717.00
$1432.00
1
(1)

Inhibits DNA synthesis and can affect cell proliferation and differentiation, potentially influencing FAM65A's function in these processes.

U-0126

109511-58-2sc-222395
sc-222395A
1 mg
5 mg
$63.00
$241.00
136
(2)

An inhibitor of MEK1/2, which are kinases involved in the MAPK/ERK pathway, potentially affecting FAM65A's function if it is part of this signaling pathway.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$88.00
$342.00
284
(5)

A p38 MAPK inhibitor, possibly affecting FAM65A activity if it is involved in stress response pathways mediated by p38 MAPK.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

An inhibitor of c-Jun N-terminal kinase (JNK), which may influence FAM65A if it plays a role in JNK-related signaling.

(S)-(−)-Blebbistatin

856925-71-8sc-204253
sc-204253A
sc-204253B
sc-204253C
1 mg
5 mg
10 mg
25 mg
$71.00
$260.00
$485.00
$949.00
(2)

Inhibits myosin II ATPase activity, potentially affecting FAM65A if it has a role in cell motility or contractility involving myosin II.

ML-7 hydrochloride

110448-33-4sc-200557
sc-200557A
10 mg
50 mg
$89.00
$262.00
13
(1)

Inhibits myosin light chain kinase (MLCK), which can affect cell shape and motility, possibly impacting FAM65A's function in these processes.