Date published: 2025-10-10

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FAM65A Inhibitors

FAM65A inhibitors are a class of chemical compounds that specifically target and inhibit the activity of the FAM65A protein, a member of the FAM65 family, which is involved in the regulation of various cellular processes, particularly those associated with cell motility, cytoskeletal dynamics, and signal transduction. FAM65A is known to interact with key components of the cytoskeleton and other regulatory proteins, playing a critical role in maintaining cell shape, facilitating cell movement, and possibly influencing the organization of cellular structures. This protein is also implicated in the regulation of signaling pathways that control cell behavior, including processes such as polarization, migration, and the response to external stimuli. The inhibition of FAM65A can therefore have significant effects on cellular architecture and function. The mechanism by which FAM65A inhibitors exert their effects typically involves binding to specific regions of the FAM65A protein, such as domains that are crucial for its interaction with other proteins or its role in cytoskeletal organization. By inhibiting FAM65A, these compounds can disrupt the normal functioning of the cytoskeleton, leading to changes in cell morphology, impaired cellular motility, and potential disruptions in signal transduction pathways. This inhibition can also affect the cell's ability to maintain its structural integrity and respond to environmental cues, which can have wide-ranging implications for cellular processes like division, migration, and tissue organization. Studying the effects of FAM65A inhibition provides valuable insights into the specific roles of this protein in cellular physiology, helping to elucidate the complex interactions that govern cytoskeletal dynamics and the overall behavior of cells within their environments. Understanding these mechanisms is crucial for advancing our knowledge of how cells regulate their shape, movement, and internal organization in response to various physiological demands.

Items 11 to 12 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Y-27632, free base

146986-50-7sc-3536
sc-3536A
5 mg
50 mg
$182.00
$693.00
88
(1)

A Rho-associated protein kinase (ROCK) inhibitor, possibly affecting FAM65A if it is involved in pathways regulating cell morphology and motility through the actin cytoskeleton.

Thapsigargin

67526-95-8sc-24017
sc-24017A
1 mg
5 mg
$94.00
$349.00
114
(2)

A sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) pump inhibitor, leading to increased cytosolic calcium levels, which could affect FAM65A function if it is calcium-sensitive.