Date published: 2025-12-23

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FAM26F Inhibitors

FAM26F inhibitors belong to a specialized class of chemical compounds designed to modulate the activity of the FAM26F protein. The FAM26F gene encodes a relatively recently discovered protein, also known as C9ORF26, characterized by its unique structure and limited understanding of its biological functions. FAM26F is primarily expressed in specific tissues, including the brain and immune system, suggesting its involvement in crucial physiological processes. The rationale behind developing FAM26F inhibitors lies in the intricate regulatory role this protein may play in cellular functions and signaling pathways. Structurally, FAM26F inhibitors exhibit distinct chemical features tailored to interact selectively with the active site of the FAM26F protein. These small molecules are meticulously designed to interfere with the protein's normal functioning, either by obstructing its binding to other cellular components or by modifying its conformation. Researchers have undertaken extensive efforts to elucidate the precise mechanisms by which FAM26F inhibitors exert their effects, aiming to unravel the intricate web of molecular interactions within the cell. Understanding the pharmacodynamics and structural nuances of these inhibitors is essential for deciphering the broader implications of modulating FAM26F activity, potentially opening avenues for future research in various biological contexts. As the scientific community continues to delve into the intricacies of FAM26F biology, the development and refinement of FAM26F inhibitors remain a focal point, holding promise for advancing our understanding of cellular processes.

Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Acetazolamide

59-66-5sc-214461
sc-214461A
sc-214461B
sc-214461C
sc-214461D
sc-214461E
sc-214461F
10 g
25 g
100 g
250 g
500 g
1 kg
2 kg
$79.00
$174.00
$425.00
$530.00
$866.00
$1450.00
$2200.00
1
(1)

Inhibits enzyme activity by binding to the zinc cofactor in the active site.

Leupeptin hemisulfate

103476-89-7sc-295358
sc-295358A
sc-295358D
sc-295358E
sc-295358B
sc-295358C
5 mg
25 mg
50 mg
100 mg
500 mg
10 mg
$72.00
$145.00
$265.00
$489.00
$1399.00
$99.00
19
(3)

Reversibly binds to and inhibits certain serine and cysteine proteases.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$121.00
$392.00
148
(1)

Inhibits kinase activity by competing with ATP for the ATP-binding site.

WZ 4002

1213269-23-8sc-364655
sc-364655A
10 mg
50 mg
$180.00
$744.00
1
(2)

Targets specific kinase domains and avoids the ATP-binding pocket, leading to selective inhibition.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$39.00
$90.00
212
(2)

Inhibits mitogen-activated protein kinase by blocking activation.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$88.00
$342.00
284
(5)

Selectively inhibits p38 MAP kinase, affecting downstream signaling.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

Inhibits c-Jun N-terminal kinase (JNK) and alters signaling pathways.

U-0126

109511-58-2sc-222395
sc-222395A
1 mg
5 mg
$63.00
$241.00
136
(2)

Selectively inhibits MEK, which is upstream of ERK in the MAPK pathway.

MG-132 [Z-Leu- Leu-Leu-CHO]

133407-82-6sc-201270
sc-201270A
sc-201270B
5 mg
25 mg
100 mg
$56.00
$260.00
$980.00
163
(3)

Reversibly inhibits the proteasome, affecting protein degradation pathways.

Aminoguanidine hydrochloride

1937-19-5sc-202931
sc-202931A
sc-202931B
10 g
25 g
50 g
$31.00
$42.00
$92.00
2
(0)

Inhibits nitric oxide synthase and the formation of advanced glycation end-products.