Date published: 2025-11-1

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FAM18B2 Inhibitors

FAM18B2 kinase inhibitors such as Staurosporine, U0126, PD98059, and LY294002 target phosphorylation events within cells. These compounds can alter signaling pathways that may control the activation state or modulate the function of FAM18B2. Cyclosporin A and Rapamycin focus on immunosuppression and growth factor signaling, respectively, and can have an impact on FAM18B2 by changing the cellular environment related to T-cell activation or cell proliferation. Calcium plays a pivotal role in numerous cellular processes, and compounds like W-7 Hydrochloride, Thapsigargin, Ionomycin, BAPTA-AM, and 2-APB can manipulate calcium signaling and homeostasis. Disruption or alteration of calcium dynamics within the cell can affect proteins that are regulated by calcium, which may include FAM18B2. MG132 affects protein turnover by inhibiting the proteasome. This action can lead to an accumulation of ubiquitinated proteins, potentially affecting the stability or interaction of FAM18B2 with other cellular proteins. These inhibitors provide insights into the protein's role in cellular functions.

Items 1 to 10 of 12 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Staurosporine

62996-74-1sc-3510
sc-3510A
sc-3510B
100 µg
1 mg
5 mg
$82.00
$150.00
$388.00
113
(4)

A kinase inhibitor that can alter phosphorylation states of proteins, potentially affecting FAM18B2-regulated signaling pathways.

Cyclosporin A

59865-13-3sc-3503
sc-3503-CW
sc-3503A
sc-3503B
sc-3503C
sc-3503D
100 mg
100 mg
500 mg
10 g
25 g
100 g
$62.00
$90.00
$299.00
$475.00
$1015.00
$2099.00
69
(5)

An immunosuppressant that can inhibit calcineurin, possibly affecting FAM18B2's role in T-cell activation.

U-0126

109511-58-2sc-222395
sc-222395A
1 mg
5 mg
$63.00
$241.00
136
(2)

A MEK inhibitor that can impede the MAPK/ERK pathway, potentially altering FAM18B2′s function if it is related to this pathway.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$121.00
$392.00
148
(1)

A PI3K inhibitor that can disrupt PI3K/Akt signaling, potentially influencing FAM18B2's activity.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$39.00
$90.00
212
(2)

Another MEK inhibitor that can block the MAPK/ERK pathway, potentially affecting FAM18B2's function.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$62.00
$155.00
$320.00
233
(4)

An mTOR inhibitor that can disrupt cell growth and proliferation signals, potentially impacting FAM18B2's function.

W-7

61714-27-0sc-201501
sc-201501A
sc-201501B
50 mg
100 mg
1 g
$163.00
$300.00
$1642.00
18
(1)

A calmodulin antagonist that can disrupt calcium signaling, potentially affecting FAM18B2 if it interacts with such pathways.

Thapsigargin

67526-95-8sc-24017
sc-24017A
1 mg
5 mg
$94.00
$349.00
114
(2)

An SERCA pump inhibitor that can disrupt calcium homeostasis, potentially affecting FAM18B2's calcium-related functions.

MG-132 [Z-Leu- Leu-Leu-CHO]

133407-82-6sc-201270
sc-201270A
sc-201270B
5 mg
25 mg
100 mg
$56.00
$260.00
$980.00
163
(3)

A proteasome inhibitor that can increase the levels of ubiquitinated proteins, potentially affecting FAM18B2's turnover or function.

Ionomycin, free acid

56092-81-0sc-263405
sc-263405A
1 mg
5 mg
$94.00
$259.00
2
(2)

A calcium ionophore that can increase intracellular calcium concentration, potentially affecting FAM18B2 if it is calcium-sensitive.