FAM18B Inhibitors
Family with sequence similarity 18 member B (FAM18B) is a protein whose function and cellular role are not yet fully elucidated. Limited information is available regarding its specific biochemical activities or interaction partners. However, based on its structural features and sequence homology, FAM18B is predicted to be involved in various cellular processes, including signal transduction, protein-protein interactions, or intracellular trafficking pathways. Its designation as a member of the FAM18 protein family suggests a role in cellular signaling cascades or regulatory networks, although experimental evidence is required to validate its precise function and biological significance.
Inhibition of FAM18B could be achieved through several strategies targeting its biochemical activities, interactions, or expression levels. One approach may involve the development of small molecule inhibitors that disrupt FAM18B's interactions with binding partners or enzymatic activities, thereby interfering with its function within cellular pathways. Alternatively, inhibition could be achieved through genetic or molecular techniques aimed at suppressing FAM18B expression levels, such as RNA interference or gene editing technologies. Furthermore, modulation of post-translational modifications or subcellular localization may also offer avenues for inhibiting FAM18B activity, as these regulatory mechanisms can influence protein function and cellular localization. Overall, elucidating the mechanisms of FAM18B inhibition will require further investigation into its biochemical properties, cellular functions, and regulatory interactions.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ouabain-d3 (Major) | sc-478417 | 1 mg | $506.00 | |||
Ouabain is an inhibitor of the Na+/K+-ATPase pump. This pump is critical in maintaining the electrochemical gradient across the cell membrane. Inhibiting this pump with Ouabain can disrupt this gradient, potentially disturbing the functional activity of FAM18B involved in ion transport. | ||||||
Verapamil | 52-53-9 | sc-507373 | 1 g | $367.00 | ||
Verapamil is a calcium channel blocker. Given that FAM18B is implicated in ion transport, the blocking of these channels by Verapamil can alter ion transport, potentially affecting the functional activity of FAM18B. | ||||||
Amiloride • HCl | 2016-88-8 | sc-3578 sc-3578A | 25 mg 100 mg | $22.00 $56.00 | 6 | |
Amiloride is an inhibitor of the Na+/H+ exchanger. This exchange mechanism is essential for maintaining cellular pH and volume, and its inhibition by Amiloride may affect the functional activity of FAM18B involved in ion transport. | ||||||
Bumetanide (Ro 10-6338) | 28395-03-1 | sc-200727 sc-200727A | 1 g 5 g | $107.00 $224.00 | 9 | |
Bumetanide is an inhibitor of the Na+/K+/2Cl- co-transporter. Given the role of FAM18B in ion transport, the inhibition of this co-transporter by Bumetanide can potentially impact the functional activity of FAM18B. | ||||||
Ethacrynic acid | 58-54-8 | sc-257424 sc-257424A | 1 g 5 g | $49.00 $229.00 | 5 | |
Ethacrynic Acid is an inhibitor of the Na+/K+/2Cl- co-transporter. Since FAM18B is involved in ion transport, the inhibition of this co-transporter by Ethacrynic Acid can potentially impact the functional activity of FAM18B. | ||||||
Glyburide (Glibenclamide) | 10238-21-8 | sc-200982 sc-200982A sc-200982D sc-200982B sc-200982C | 1 g 5 g 25 g 100 g 500 g | $45.00 $60.00 $115.00 $170.00 $520.00 | 36 | |
Glibenclamide is an ATP-sensitive potassium channel blocker. Given that FAM18B is implicated in ion transport, the blocking of these channels by Glibenclamide can alter ion transport, potentially affecting the functional activity of FAM18B. | ||||||
Nifedipine | 21829-25-4 | sc-3589 sc-3589A | 1 g 5 g | $58.00 $170.00 | 15 | |
Nifedipine is a calcium channel blocker. FAM18B has been implicated in the regulation of ion transport, and the inhibition of these channels by Nifedipine can lead to altered ion transport, potentially affecting the functional activity of FAM18B. | ||||||
Tetraethylammonium chloride | 56-34-8 | sc-202834 | 25 g | $44.00 | 2 | |
Tetraethylammonium is a voltage-gated potassium channel blocker. Given the role of FAM18B in ion transport, the blocking of these channels by Tetraethylammonium can alter ion transport, potentially affecting the functional activity of FAM18B. | ||||||
Diltiazem | 42399-41-7 | sc-204726 sc-204726A | 1 g 5 g | $209.00 $464.00 | 4 | |
Diltiazem is a calcium channel blocker. Since FAM18B is involved in ion transport, the inhibition of these channels by Diltiazem can lead to altered ion transport, potentially affecting the functional activity of FAM18B. | ||||||
Quinidine | 56-54-2 | sc-212614 | 10 g | $102.00 | 3 | |
Quinidine is a voltage-gated sodium channel blocker. Given that FAM18B is implicated in ion transport, the blocking of these channels by Quinidine can alter ion transport, potentially affecting the functional activity of FAM18B. | ||||||