Family with sequence similarity 18 member B (FAM18B) is a protein whose functional role and regulatory mechanisms remain largely elusive within the current scientific literature. Despite being a member of the FAM18 protein family, its specific biochemical activities, cellular functions, and involvement in biological processes have yet to be fully characterized. The lack of available information hinders a comprehensive understanding of FAM18B's role in cellular physiology, signaling pathways, or molecular interactions. However, based on its sequence homology and structural features, FAM18B is speculated to participate in various cellular processes, including signal transduction, protein-protein interactions, or intracellular trafficking pathways. Additionally, the designation as a member of a protein family implies functional similarities or conserved roles across family members, suggesting that FAM18B may play a role in cellular signaling cascades or regulatory networks akin to other members of the FAM18 family. Nonetheless, experimental validation is necessary to decipher the precise biochemical activities and functional significance of FAM18B within the context of cellular physiology and molecular biology.
Activation mechanisms governing FAM18B's function are currently unknown due to the lack of available experimental data and characterization. However, activation of proteins within cellular pathways typically involves a series of regulatory events that modulate protein expression, post-translational modifications, and protein-protein interactions. These mechanisms may include transcriptional regulation of FAM18B gene expression in response to cellular stimuli or signaling pathways, leading to increased protein levels and subsequent activation. Furthermore, post-translational modifications such as phosphorylation, acetylation, or ubiquitination may regulate FAM18B's enzymatic activities, protein stability, subcellular localization, or interactions with binding partners, thereby influencing its functional state. Additionally, activation of FAM18B may be modulated by cellular signaling cascades, protein-protein interactions, or environmental cues, further regulating its participation in cellular processes and molecular pathways. Further investigation is warranted to unravel the specific mechanisms governing FAM18B activation and its role in cellular physiology and molecular biology.
SEE ALSO...
Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
---|---|---|---|---|---|---|
Calcium dibutyryladenosine cyclophosphate | 362-74-3 | sc-482205 | 25 mg | $147.00 | ||
Dibutyryl cAMP is a cell-permeable cAMP analog that activates cAMP-dependent proteins. As FAM18B is a cAMP-dependent protein, dibutyryl cAMP can directly enhance the activity of FAM18B. | ||||||
(−)-Epinephrine | 51-43-4 | sc-205674 sc-205674A sc-205674B sc-205674C sc-205674D | 1 g 5 g 10 g 100 g 1 kg | $40.00 $102.00 $197.00 $1739.00 $16325.00 | ||
Epinephrine binds to beta-adrenergic receptors, triggering a signaling cascade that increases cAMP levels. As FAM18B is a cAMP-dependent protein, the increased cAMP levels can enhance the activity of FAM18B. | ||||||
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $27.00 $37.00 | 5 | |
Isoproterenol is a nonselective beta-adrenergic agonist that increases intracellular cAMP levels. As FAM18B is a cAMP-dependent protein, increased cAMP levels can enhance the activity of FAM18B. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $75.00 $212.00 | 18 | |
Rolipram inhibits phosphodiesterase 4 (PDE4), an enzyme that breaks down cAMP, leading to increased intracellular levels of cAMP. As FAM18B is a cAMP-dependent protein, the increased cAMP levels can enhance the activity of FAM18B. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $159.00 $315.00 $598.00 | 34 | |
IBMX is a nonspecific inhibitor of phosphodiesterase, preventing the breakdown of cAMP and thereby increasing its intracellular levels. As FAM18B is a cAMP-dependent protein, the increased cAMP levels can enhance the activity of FAM18B. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $56.00 $156.00 $270.00 $665.00 | 37 | |
Prostaglandin E2 (PGE2) activates Epac, a guanine nucleotide exchange factor directly activated by cAMP. Thus, PGE2 indirectly enhances the activity of FAM18B by promoting cAMP production. | ||||||
8-Bromo-cAMP | 76939-46-3 | sc-201564 sc-201564A | 10 mg 50 mg | $97.00 $224.00 | 30 | |
8-Bromo-cAMP is a cell-permeable cAMP analog that activates cAMP-dependent proteins. As FAM18B is a cAMP-dependent protein, 8-Bromo-cAMP can directly enhance the activity of FAM18B. | ||||||
8-CPT-cAMP | 93882-12-3 | sc-201569 sc-201569A | 20 mg 100 mg | $85.00 $310.00 | 19 | |
8-CPT-cAMP is a cell-permeable cAMP analog that activates cAMP-dependent proteins. It can directly enhance the activity of FAM18B, which is a cAMP-dependent protein. | ||||||
Theophylline | 58-55-9 | sc-202835 sc-202835A sc-202835B | 5 g 25 g 100 g | $20.00 $31.00 $83.00 | 6 | |
Theophylline is a phosphodiesterase inhibitor that increases intracellular cAMP levels. As FAM18B is a cAMP-dependent protein, the increased cAMP levels can directly enhance the activity of FAM18B. | ||||||
Papaverine | 58-74-2 | sc-279951 sc-279951A sc-279951B | 10 mg 50 mg 100 mg | $153.00 $265.00 $459.00 | ||
Papaverine is a phosphodiesterase inhibitor that increases intracellular cAMP levels. As FAM18B is a cAMP-dependent protein, the increased cAMP levels can directly enhance the activity of FAM18B. |