Forskolin and PGE2 primarily target adenylate cyclase and EP receptors respectively, both of which lead to an increase in cAMP levels and thereby can activate cAMP-dependent pathways that include FAM184A. Epidermal Growth Factor (EGF) operates by activating the EGF receptor and initiating phosphorylation cascades that can contribute to increased FAM184A activity. Ionomycin, by elevating intracellular calcium, triggers calcium-dependent pathways that can involve FAM184A. LY294002 acts by inhibiting PI3K, thereby lifting negative feedback loops that might otherwise restrain FAM184A, leading to its activation.
Retinoic Acid and 5-Azacytidine operate at the level of gene expression and epigenetic regulation, thereby affecting FAM184A levels. Quercetin, known to activate the JNK pathway, increases FAM184A by affecting phosphorylation events. Trichostatin A, an HDAC inhibitor, can change the epigenetic landscape to favor FAM184A upregulation. L-Ascorbic acid, Estradiol, and Isoformononetin have specific pathway targets that can trigger downstream effects, such as collagen production and AMPK and estrogen receptor activation, which can culminate in increased FAM184A activity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ionomycin, free acid | 56092-81-0 | sc-263405 sc-263405A | 1 mg 5 mg | $94.00 $259.00 | 2 | |
Raises intracellular calcium levels, which can trigger pathways involving FAM184A. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $56.00 $156.00 $270.00 $665.00 | 37 | |
Activates EP receptors and downstream cAMP production, which can lead to enhanced FAM184A activity. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Inhibits PI3K, disrupting negative feedback that restrains FAM184A, thereby potentially elevating its activity. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Upregulates FAM184A through gene expression modulation via nuclear receptors. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
DNA methyltransferase inhibitor; upregulates FAM184A through epigenetic control mechanisms. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Known to activate the JNK pathway, which can elevate FAM184A by affecting phosphorylation events. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
HDAC inhibitor; can upregulate FAM184A through epigenetic alteration of histone acetylation. | ||||||
L-Ascorbic acid, free acid | 50-81-7 | sc-202686 | 100 g | $45.00 | 5 | |
Increases collagen production, potentially raising FAM184A levels that may be involved in cellular matrix formation. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $62.00 $178.00 | 8 | |
Activates estrogen receptors; can trigger downstream pathways that lead to elevated FAM184A activity. | ||||||